24VA image
Deposition Date 2026-03-22
Release Date 2026-11-11
Last Version Date 2026-11-11
Entry Detail
PDB ID:
24VA
Keywords:
TOXIN
Title:
Cryo-EM structure of recombinant Botulinum neurotoxin A
Biological Source:
Source Organism(s):
Clostridium botulinum (strain Hall / ATCC 3502 / NCTC 13319 / Type A) (Taxon ID: 441771)
Expression System(s):
Escherichia coli
Method Details:
Experimental Method:
ELECTRON MICROSCOPY
Resolution:
3.24 Å
Aggregation State:
PARTICLE
Reconstruction Method:
SINGLE PARTICLE
24VA validation report missing
Macromolecular Entities
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Botulinum neurotoxin type A
Gene (Uniprot):botA
Chain IDs:A
Chain Length:448
Number of Molecules:1
Biological Source:Clostridium botulinum (strain Hall / ATCC 3502 / NCTC 13319 / Type A)
UniProt ID:P0DPI1 EC:3.4.24.69
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Botulinum neurotoxin A heavy
Gene (Uniprot):botA
Chain IDs:B
Chain Length:850
Number of Molecules:1
Biological Source:Clostridium botulinum (strain Hall / ATCC 3502 / NCTC 13319 / Type A)
UniProt ID:P0DPI1 EC:3.4.24.69
Ligand Molecules
NA
Primary Citation
Recombinant versus native botulinum neurotoxin type A: structural and pharmacodynamic comparison.
Acta Crystallogr.,Sect.F 82 391 401 (2026)
PMID: 42911674 DOI: 10.1107/S2053230X26009830
Primary Citation of related structures
24VA
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