ISDA: 24UO

Deposition Date 2026-03-21

Release Date 2026-10-28

Last Version Date 2026-10-28

Entry Detail

PDB ID:

24UO

Keywords:

TRANSPORT PROTEIN

Title:

Cryo-EM structure of AcrB in liposomes incubated with doxorubicin (class2-out)

Biological Source:

Source Organism(s):

Escherichia coli K-12 (Taxon ID: 83333)

Expression System(s):

Escherichia coli bl21

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

3.75 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

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Macromolecular Entities

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Multidrug efflux pump subunit
Gene (Uniprot):acrB
Chain IDs:A (auth: B), B (auth: C), C (auth: A)
Chain Length:1049
Number of Molecules:3
Biological Source:Escherichia coli K-12

UniProt ID:P31224

Ligand Molecules

Primary Citation

Cryo-EM structural analysis of liposome-reconstituted AcrB in the presence of substrates.

Akisada, S, Sakaguchi, W, Nakano, A, Muto, Y, Mitsuoka, K, Yokoyama, K.Show

J.Struct.Biol. 218 108367 108367 (2026)

PMID: 42668048 DOI: 10.1016/j.jsb.2026.108367

Primary Citation of related structures

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