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Deposition Date 2026-03-17
Release Date 2026-05-27
Last Version Date 2026-05-27
Entry Detail
PDB ID:
24RC
Keywords:
MEMBRANE PROTEIN
Title:
Cryo-EM structure of human sodium pump W931R mutant in K+-occluded E2-Pi state
Biological Source:
Source Organism(s):
Homo sapiens (Taxon ID: 9606)
Expression System(s):
Homo sapiens
Method Details:
Experimental Method:
ELECTRON MICROSCOPY
Resolution:
2.61 Å
Aggregation State:
PARTICLE
Reconstruction Method:
SINGLE PARTICLE
24RC validation report missing
Macromolecular Entities
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Sodium/potassium-transporting
Gene (Uniprot):ATP1A1
Mutagens:W931R
Chain IDs:A
Chain Length:984
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:P05023 Pfam ID:PF00690, PF00122, PF13246, PF00689 EC:7.2.2.3
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Sodium/potassium-transporting
Gene (Uniprot):ATP1B3
Chain IDs:B
Chain Length:268
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:P54709 Pfam ID:PF00287
Ligand Molecules
ALF
CLR
K
MG
PCW
Primary Citation
On the mechanism of hypomagnesimia with treatment-resistant seizures cansed by variants of the Na+,K+-ATPase alpha1 subunit (ATP1A1)
To Be Published ? ? ? (?)
Primary Citation of related structures
24RC
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