ISDA: 24PV

Deposition Date 2026-03-16

Release Date 2026-09-23

Last Version Date 2026-09-23

Entry Detail

PDB ID:

24PV

Keywords:

DNA BINDING PROTEIN

Title:

The crystal structure of the chicken MHF1-MHF2(L77C) disulfide-crosslinked complex

Biological Source:

Source Organism(s):

Gallus gallus (Taxon ID: 9031)

Expression System(s):

Escherichia coli b

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

4.00 Å

R-Value Free:

0.33

R-Value Work:

0.25

R-Value Observed:

0.26

Space Group:

C 2 2 21

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Macromolecular Entities

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Centromere protein S
Gene (Uniprot):CENPS
Mutagens:C26A, C28A, C55A
Chain IDs:A, C, E, G
Chain Length:0
Number of Molecules:4
Biological Source:Gallus gallus

UniProt ID:E1BSW7 Pfam ID:PF15630

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Centromere protein X
Gene (Uniprot):CENPX
Mutagens:L77C
Chain IDs:B, D, F, H
Chain Length:0
Number of Molecules:4
Biological Source:Gallus gallus

UniProt ID:P0DJH7 Pfam ID:PF09415

Ligand Molecules

Primary Citation

Disulfide engineering of the FANCM-MHF complex reveals constraints on crosslink design in symmetric oligomers.

Ito, S, Nishino, T.Show

Protein Sci. 35 e70761 e70761 (2026)

PMID: 42606197 DOI: 10.1002/pro.70761

Primary Citation of related structures

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