ISDA: 24PU

Deposition Date 2026-03-16

Release Date 2026-09-23

Last Version Date 2026-09-23

Entry Detail

PDB ID:

24PU

Keywords:

DNA BINDING PROTEIN

Title:

The crystal structure of the chicken FANCM-MHF1-MHF2(Q74C) disulfide-crosslinked complex

Biological Source:

Source Organism(s):

Gallus gallus (Taxon ID: 9031)

Expression System(s):

Escherichia coli b

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

2.40 Å

R-Value Free:

0.27

R-Value Work:

0.20

R-Value Observed:

0.21

Space Group:

P 21 21 21

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Macromolecular Entities

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Centromere protein S
Gene (Uniprot):CENPS
Mutagens:C26A, C28A, C55A
Chain IDs:A, B
Chain Length:0
Number of Molecules:2
Biological Source:Gallus gallus

UniProt ID:E1BSW7 Pfam ID:PF15630

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Centromere protein X
Gene (Uniprot):CENPX
Mutagens:L77C
Chain IDs:D (auth: C), E (auth: D)
Chain Length:0
Number of Molecules:2
Biological Source:Gallus gallus

UniProt ID:P0DJH7 Pfam ID:PF09415

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Fanconi anemia group M protei
Gene (Uniprot):FANCM
Chain IDs:C (auth: E)
Chain Length:0
Number of Molecules:1
Biological Source:Gallus gallus

UniProt ID:A0A1D5PRR9 Pfam ID:PF16783 EC:3.6.4.13

Primary Citation

Disulfide engineering of the FANCM-MHF complex reveals constraints on crosslink design in symmetric oligomers.

Ito, S, Nishino, T.Show

Protein Sci. 35 e70761 e70761 (2026)

PMID: 42606197 DOI: 10.1002/pro.70761

Primary Citation of related structures

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