23OI image
Deposition Date 2026-02-11
Release Date 2026-07-01
Last Version Date 2026-07-01
Entry Detail
PDB ID:
23OI
Keywords:
MEMBRANE PROTEIN
Title:
Cryo-EM structure of the cebranopadol-NOP receptor-Gi complex
Biological Source:
Source Organism(s):
Rattus norvegicus (Taxon ID: 10116)
Bos taurus (Taxon ID: 9913)
Homo sapiens (Taxon ID: 9606)
Expression System(s):
Spodoptera frugiperda
Method Details:
Experimental Method:
ELECTRON MICROSCOPY
Resolution:
2.74 Å
Aggregation State:
PARTICLE
Reconstruction Method:
SINGLE PARTICLE
23OI validation report missing
Macromolecular Entities
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Guanine nucleotide-binding pr
Gene (Uniprot):GNAI1
Mutagens:G203A, A326S
Chain IDs:D (auth: A)
Chain Length:354
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:P63096 Pfam ID:PF00503
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Guanine nucleotide-binding pr
Gene (Uniprot):Gnb1
Chain IDs:A (auth: B)
Chain Length:345
Number of Molecules:1
Biological Source:Rattus norvegicus
UniProt ID:P54311 Pfam ID:PF25391
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Guanine nucleotide-binding pr
Gene (Uniprot):GNG2
Chain IDs:B (auth: C)
Chain Length:68
Number of Molecules:1
Biological Source:Bos taurus
UniProt ID:P63212 Pfam ID:PF00631
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Nociceptin receptor
Gene (Uniprot):OPRL1
Chain IDs:C (auth: R)
Chain Length:370
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:P41146 Pfam ID:PF00001
Ligand Molecules
A1E5L
Primary Citation
Cryo-EM structure of the cebranopadol-NOP receptor-Gi complex
To Be Published ? ? ? (?)
Primary Citation of related structures
23OI
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