ISDA: 23KA

Deposition Date 2026-02-09

Release Date 2026-05-06

Last Version Date 2026-05-06

Entry Detail

PDB ID:

23KA

Keywords:

RNA

Title:

pre-miR-6074 internal loop in complex with amiloride (Form 2)

Biological Source:

Source Organism(s):

synthetic construct (Taxon ID: 32630)

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

2.59 Å

R-Value Free:

0.21

R-Value Work:

0.18

R-Value Observed:

0.18

Space Group:

P 32

Download Validation Report

Macromolecular Entities

Polymer Type:polyribonucleotide
Molecule:RNA (35-MER)
Chain IDs:A, B, C
Chain Length:35
Number of Molecules:3
Biological Source:synthetic construct

Ligand Molecules

AMR

CAD

Primary Citation

RNA-binding Landscape of Amiloride: Large-scale Profiling and Structural Basis of U-U Mismatch Recognition

Tsuzuki, K, Onizuka, K, Okada, M, Nagasawa, R, Miyashita, E, Komatsu, K.R, Saito, H, Kondo, J, Nagatsugi, F.Show

Rsc Chem Biol ? ? ? (2025)

DOI: 10.1039/D6CB00055J

Primary Citation of related structures

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