ISDA: 23FQ

Deposition Date 2026-02-05

Release Date 2026-09-09

Last Version Date 2026-09-09

Entry Detail

PDB ID:

23FQ

Keywords:

DE NOVO PROTEIN

Title:

Dipeptide removal from MccJ25 yields a new lasso peptide delta-VG

Biological Source:

Source Organism(s):

Escherichia coli (Taxon ID: 562)

Method Details:

Experimental Method:

SOLUTION NMR

Conformers Calculated:

Conformers Submitted:

Selection Criteria:

all calculated structures submitted

Download Validation Report

Macromolecular Entities

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Microcin J25
Gene (Uniprot):mcjA
Chain IDs:A
Chain Length:19
Number of Molecules:1
Biological Source:Escherichia coli

UniProt ID:Q9X2V7

Ligand Molecules

Primary Citation

Chemoenzymatic Modification of Microcin J25 with Single-Residue Precision Provides New-to-Nature Lasso Peptides.

Tsai, C.Y, Chung, H.W, Huang, Y.P, Chang, C.F, Cheung, K.Y, Tan, H.N, Huang, H.Y, Sung, L.K, Hegemann, J.D, Chan, Y.T, Chu, J.Show

Jacs Au 6 4618 4625 (2026)

PMID: 42657259 DOI: 10.1021/jacsau.6c00700

Primary Citation of related structures

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