ISDA: 22TZ

Deposition Date 2026-01-23

Release Date 2026-07-29

Last Version Date 2026-07-29

Entry Detail

PDB ID:

22TZ

Keywords:

BIOSYNTHETIC PROTEIN

Title:

Crystal structure of AstC in complex with farnesyl pyrophosphate

Biological Source:

Source Organism(s):

Aspergillus oryzae (Taxon ID: 5062)

Expression System(s):

Escherichia coli

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

2.96 Å

R-Value Free:

0.22

R-Value Work:

0.17

R-Value Observed:

0.17

Space Group:

P 21 21 21

Download Validation Report

Macromolecular Entities

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:AstC
Chain IDs:A, B
Chain Length:488
Number of Molecules:2
Biological Source:Aspergillus oryzae

Ligand Molecules

EPE

FPP

Primary Citation

Dimerization-Dependent Trans-Domain Coupling Enables Intermediate Transfer in Fungal Haloacid Dehalogenase-Like Terpene Cyclases.

Chen, T.H, Huang, K.F, Chou, T.H, Tseng, C.C, Huang, R.J, Ko, T.P, Liang, S.Y, Chein, R.J, Lin, H.C.Show

J.Am.Chem.Soc. 148 22120 22130 (2026)

PMID: 42139319 DOI: 10.1021/jacs.6c04151

Primary Citation of related structures

Feedback Form