22JZ image
Deposition Date 2026-01-14
Release Date 2026-09-09
Last Version Date 2026-09-09
Entry Detail
PDB ID:
22JZ
Keywords:
MEMBRANE PROTEIN/IMMUNE SYSTEM
Title:
Cryo-EM structure of the mGlu7-beta-arrestin 1 complex
Biological Source:
Source Organism(s):
Homo sapiens (Taxon ID: 9606)
Mus musculus (Taxon ID: 10090)
Expression System(s):
Spodoptera frugiperda
Method Details:
Experimental Method:
ELECTRON MICROSCOPY
Resolution:
3.40 Å
Aggregation State:
PARTICLE
Reconstruction Method:
SINGLE PARTICLE
22JZ validation report missing
Macromolecular Entities
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Isoform 4 of Metabotropic glu
Gene (Uniprot):GRM7
Chain IDs:A, B
Chain Length:909
Number of Molecules:2
Biological Source:Homo sapiens
UniProt ID:Q14831 Pfam ID:PF01094, PF07562, PF00003
Polymer Type:polypeptide(L)
Molecule:beta-arrestin 1
Mutagens:R169E
Chain IDs:C, E
Chain Length:505
Number of Molecules:2
Biological Source:Homo sapiens
Polymer Type:polypeptide(L)
Molecule:scFv30
Chain IDs:D
Chain Length:111
Number of Molecules:1
Biological Source:Mus musculus
Ligand Molecules
CLR
GLU
Primary Citation
Subtype-dependent arrestin engagement of the metabotropic glutamate receptors
To be published ? ? ? (?)
Primary Citation of related structures
22JZ
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