ISDA: 21RT

Deposition Date 2025-12-23

Release Date 2026-09-16

Last Version Date 2026-09-16

Entry Detail

PDB ID:

21RT

Keywords:

IMMUNE SYSTEM

Title:

Cryo-EM structure of mouse myeloperoxidase in complex with Fab fragments of antibodies mAb-A46 and mAb-B88

Biological Source:

Source Organism(s):

Mus musculus (Taxon ID: 10090)

Expression System(s):

Homo sapiens, Mus musculus

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

2.95 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

Download Validation Report

Macromolecular Entities

Polymer Type:polypeptide(L)
Molecule:mAb-A46 Fab Heavy chain
Chain IDs:A
Chain Length:224
Number of Molecules:1
Biological Source:Mus musculus

Polymer Type:polypeptide(L)
Molecule:mAb-A46 Fab Light chain
Chain IDs:B
Chain Length:213
Number of Molecules:1
Biological Source:Mus musculus

Polymer Type:polypeptide(L)
Molecule:mAb-B88 Fab Heavy chain
Chain IDs:C
Chain Length:224
Number of Molecules:1
Biological Source:Mus musculus

Polymer Type:polypeptide(L)
Molecule:mAb-B88 Fab Light chain
Chain IDs:D
Chain Length:214
Number of Molecules:1
Biological Source:Mus musculus

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Myeloperoxidase light chain
Gene (Uniprot):Mpo
Chain IDs:E
Chain Length:114
Number of Molecules:1
Biological Source:Mus musculus

UniProt ID:P11247 EC:1.11.2.2

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Myeloperoxidase
Gene (Uniprot):Mpo
Chain IDs:F
Chain Length:476
Number of Molecules:1
Biological Source:Mus musculus

UniProt ID:Q6RFG4 EC:1.11.2.2

Ligand Molecules