ISDA: 13AM

Deposition Date 2026-04-27

Release Date 2026-11-11

Last Version Date 2026-11-11

Entry Detail

PDB ID:

13AM

Keywords:

IMMUNE SYSTEM

Title:

Crystal Structure of Human IGG1 FC Fragment (P33A, Orthorhombic P Form)

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)

Expression System(s):

Komagataella pastoris

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

1.60 Å

R-Value Free:

0.21

R-Value Work:

0.18

R-Value Observed:

0.18

Space Group:

P 21 21 21

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Macromolecular Entities

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Hepatitis B virus receptor bi
Mutagens:P33A
Chain IDs:A, B
Chain Length:223
Number of Molecules:2
Biological Source:Homo sapiens

UniProt ID:Q6PYX1

Ligand Molecules

GOL

Primary Citation

Near UV Photo-Degradation of IgG1-Fc Promoted by His and Fe(III): Probing the Role of the Metal-Binding Pocket by Site-Directed Mutagenesis.

Ballesteros, M.E, Rodriguez, M.S, Seibold, S, Battaile, K.P, Lovell, S, Tolbert, T.J, Schoneich, C.Show

Mol Pharm. 23 5489 5501 (2026)

PMID: 42969716 DOI: 10.1021/acs.molpharmaceut.6c00605

Primary Citation of related structures

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