12QJ image
Deposition Date 2026-04-15
Release Date 2026-06-03
Last Version Date 2026-06-03
Entry Detail
PDB ID:
12QJ
Keywords:
IMMUNE SYSTEM
Title:
Pneumococcal choline binding CbpE surface protein bounds to 5992-2 Fab
Biological Source:
Source Organism(s):
Streptococcus pneumoniae (Taxon ID: 1313)
Homo sapiens (Taxon ID: 9606)
Expression System(s):
Escherichia coli 'bl21-gold(de3)plyss ag', Homo sapiens
Method Details:
Experimental Method:
ELECTRON MICROSCOPY
Resolution:
3.35 Å
Aggregation State:
PARTICLE
Reconstruction Method:
SINGLE PARTICLE
12QJ validation report missing
Macromolecular Entities
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Choline binding protein E Cbp
Gene (Uniprot):lytB_3
Chain IDs:A
Chain Length:394
Number of Molecules:1
Biological Source:Streptococcus pneumoniae
UniProt ID:A0A0T8F9T1 EC:3.2.1.96
Protein Blast
Polymer Type:polypeptide(L)
Molecule:5992-2 Fab Heavy Chain
Chain IDs:B
Chain Length:125
Number of Molecules:1
Biological Source:Homo sapiens
Protein Blast
Polymer Type:polypeptide(L)
Molecule:5992-2 Fab Light Chain
Chain IDs:C
Chain Length:111
Number of Molecules:1
Biological Source:Homo sapiens
Ligand Molecules
NA
Primary Citation
BROADLY REACTIVE HUMAN MONOCLONAL ANTIBODY TARGETING CONSERVED PNEUMOCOCCAL CHOLINE BINDING DOMAIN INCREASES PROTECTION AGAINST LETHAL PNEUMOCOCCAL INFECTION
To Be Published ? ? ? (?)
Primary Citation of related structures
12QJ
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