ISDA: 12FE

Deposition Date 2026-04-01

Release Date 2026-05-27

Last Version Date 2026-05-27

Entry Detail

PDB ID:

12FE

Keywords:

IMMUNE SYSTEM

Title:

Crystal structure of unliganded Fab 399

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)

Expression System(s):

Cricetulus griseus

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

2.29 Å

R-Value Free:

0.27

R-Value Work:

0.24

R-Value Observed:

0.24

Space Group:

P 1 21 1

Download Validation Report

Macromolecular Entities

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Heavy Chain of Fab 399
Chain IDs:B (auth: A), C
Chain Length:224
Number of Molecules:2
Biological Source:Homo sapiens

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Light Chain of Fab 399
Chain IDs:A (auth: L), D (auth: B)
Chain Length:219
Number of Molecules:2
Biological Source:Homo sapiens

Primary Citation

Structural basis for conserved and distinct antigen recognition by a lineage of malaria-protective antibodies

Jain, M, Wilson, I.A.Show

Plos Pathog. ? ? ? (2026)

Primary Citation of related structures

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