12CL image
Deposition Date 2026-03-26
Release Date 2026-07-29
Last Version Date 2026-07-29
Entry Detail
PDB ID:
12CL
Keywords:
OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR
Title:
Crystal structure of canine myeloperoxidase inhibited by SPIN from Staphylococcus delphini
Biological Source:
Source Organism(s):
Staphylococcus delphini (Taxon ID: 53344)
Canis lupus familiaris (Taxon ID: 9615)
Expression System(s):
Escherichia coli bl21(de3)
Method Details:
Experimental Method:
X-RAY DIFFRACTION
Resolution:
2.10 Å
R-Value Free:
0.19
R-Value Work:
0.16
R-Value Observed:
0.16
Space Group:
C 1 2 1
12CL validation report missing
Macromolecular Entities
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Myeloperoxidase
Gene (Uniprot):MPO
Chain IDs:A, B
Chain Length:741
Number of Molecules:2
Biological Source:Canis lupus familiaris
UniProt ID:A0A8I3P7A7 Pfam ID:PF03098 EC:1.11.2.2
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:SPIN family peroxidase inhibi
Gene (Uniprot):B5C08_06775
Chain IDs:C, D
Chain Length:77
Number of Molecules:2
Biological Source:Staphylococcus delphini
UniProt ID:A0A2A4GXB5
Ligand Molecules
ACT
CA
CL
GOL
HEM
NAG
SO4
Primary Citation
Staphylococcal Peroxidase Inhibitor: Structure/Function Studies on Host-Species Specificity
To Be Published ? ? ? (?)
Primary Citation of related structures
12CL
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