ISDA: 12CI

Deposition Date 2026-03-26

Release Date 2026-05-13

Last Version Date 2026-05-13

Entry Detail

PDB ID:

12CI

Keywords:

RNA

Title:

Structure of dopamine-binding aptamer, DGR-1A, in complex with dopamine

Biological Source:

Source Organism(s):

synthetic construct (Taxon ID: 32630)

Expression System(s):

Synthetic construct

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

2.59 Å

R-Value Free:

0.27

R-Value Work:

0.22

R-Value Observed:

0.22

Space Group:

P 1 21 1

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Macromolecular Entities

Polymer Type:polyribonucleotide
Molecule:DGR-1A aptamer
Chain IDs:A, B
Chain Length:82
Number of Molecules:2
Biological Source:synthetic construct

Ligand Molecules

LDP

NCO

Primary Citation

Structural characterization of a dopamine-binding aptamer raised through scaffolded selection

Siwik, S.H, Batey, R.T.Show

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