ISDA: 11ZU

Deposition Date 2026-03-20

Release Date 2026-09-02

Last Version Date 2026-09-02

Entry Detail

PDB ID:

11ZU

Keywords:

PROTEIN BINDING

Title:

Covalent stabilizer compound 7 for the interaction between 14-3-3 sigma and Estrogen receptor-alpha peptide

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)

Expression System(s):

Escherichia coli

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

2.25 Å

R-Value Free:

0.22

R-Value Work:

0.18

R-Value Observed:

0.18

Space Group:

C 2 2 21

Download Validation Report

Macromolecular Entities

Polymer Type:polypeptide(L)
Molecule:14-3-3 protein sigma
Chain IDs:A, B (auth: C)
Chain Length:253
Number of Molecules:2
Biological Source:Homo sapiens

Polymer Type:polypeptide(L)
Molecule:Estrogen receptor
Chain IDs:C (auth: X), D (auth: Y)
Chain Length:15
Number of Molecules:2
Biological Source:Homo sapiens

Modified Residue