9Y7E image
Deposition Date 2025-09-09
Release Date 2026-08-26
Last Version Date 2026-08-26
Entry Detail
PDB ID:
9Y7E
Keywords:
PROTEIN BINDING
Title:
Covalent stabilizer of the interaction between 14-3-3 sigma and Estrogen receptor-alpha peptide
Biological Source:
Source Organism(s):
Homo sapiens (Taxon ID: 9606)
Expression System(s):
Escherichia coli
Method Details:
Experimental Method:
X-RAY DIFFRACTION
Resolution:
2.28 Å
R-Value Free:
0.26
R-Value Work:
0.23
R-Value Observed:
0.23
Space Group:
C 2 2 21
9Y7E validation report missing
Macromolecular Entities
Polymer Type:polypeptide(L)
Molecule:14-3-3 protein sigma
Chain IDs:A, B (auth: C)
Chain Length:248
Number of Molecules:2
Biological Source:Homo sapiens
Polymer Type:polypeptide(L)
Molecule:Estrogen receptor Alpha Pepti
Chain IDs:C (auth: X), D (auth: Y)
Chain Length:15
Number of Molecules:2
Biological Source:Homo sapiens
Modified Residue
Compound ID Chain ID Parent Comp ID Details 2D Image
TPO C THR modified residue
Ligand Molecules
A1CSY
Primary Citation
Covalent Stabilizers of the Interaction Between 14-3-3 sigma
Acs Med.Chem.Lett. ? ? ? (2026)
DOI: 10.1021/acsmedchemlett.6c00325
Primary Citation of related structures
9Y7E
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