ISDA: 11ZJ

Deposition Date 2026-03-19

Release Date 2026-08-19

Last Version Date 2026-08-19

Entry Detail

PDB ID:

11ZJ

Keywords:

RNA BINDING PROTEIN/RNA

Title:

Structure of AGO2 RISC with an 18-nt target

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)

Expression System(s):

Trichoplusia ni

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

3.29 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

Download Validation Report

Macromolecular Entities

Polymer Type:polypeptide(L)
Molecule:Protein argonaute-2
Chain IDs:C (auth: A)
Chain Length:864
Number of Molecules:1
Biological Source:Homo sapiens

Polymer Type:polyribonucleotide
Molecule:RNA (5'-R(P*UP*AP*AP*AP*GP*UP
Chain IDs:A (auth: B)
Chain Length:23
Number of Molecules:1
Biological Source:Homo sapiens

Polymer Type:polyribonucleotide
Molecule:RNA (5'-R(P*CP*AP*CP*UP*AP*(O
Chain IDs:B (auth: C)
Chain Length:18
Number of Molecules:1
Biological Source:Homo sapiens

Ligand Molecules

Primary Citation

Structure of AGO2 RISC with an 18-nt target

Zhang, H, Nakanishi, K.Show

To Be Published ? ? ? (?)

Primary Citation of related structures

Feedback Form