ISDA: 10BE

Deposition Date 2026-01-09

Release Date 2026-06-03

Last Version Date 2026-06-03

Entry Detail

PDB ID:

10BE

Keywords:

RNA BINDING PROTEIN

Title:

Human AGO2 bound to a miR-20a guide and a position 10-11 mismatched target

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)

Expression System(s):

Trichoplusia ni

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

3.02 Å

Aggregation State:

CELL

Reconstruction Method:

SINGLE PARTICLE

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Macromolecular Entities

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Protein argonaute-2
Gene (Uniprot):AGO2
Chain IDs:C (auth: A)
Chain Length:873
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:Q9UKV8 Pfam ID:PF16486, PF08699, PF02170, PF16488, PF16487, PF02171 EC:3.1.26.-

Polymer Type:polyribonucleotide
Molecule:Guide RNA
Chain IDs:A (auth: B)
Chain Length:23
Number of Molecules:1
Biological Source:Homo sapiens

Polymer Type:polyribonucleotide
Molecule:Target RNA
Chain IDs:B (auth: C)
Chain Length:18
Number of Molecules:1
Biological Source:Homo sapiens

Ligand Molecules

Primary Citation

Human AGO2 bound to a miR-20a guide and position 10-11 mismatched target

Zhang, H, Annasaheb-Adhav, V, Kehling, C, Savidge, A, Shen, Z, Fu, T.M, Nakanishi, K.Show

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Primary Citation of related structures

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