ISDA: 11XU

Deposition Date 2026-03-17

Release Date 2026-09-09

Last Version Date 2026-09-09

Entry Detail

PDB ID:

11XU

Keywords:

STRUCTURAL PROTEIN

Title:

In situ subtomogram average of the transition zone linker in human airway cilia (composite map)

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

9.60 Å

Aggregation State:

CELL

Reconstruction Method:

SUBTOMOGRAM AVERAGING

Download Validation Report

Macromolecular Entities

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Epithelial cell-transforming
Gene (Uniprot):ECT2L
Chain IDs:A (auth: A1), B (auth: B1)
Chain Length:904
Number of Molecules:2
Biological Source:Homo sapiens

UniProt ID:Q008S8 Pfam ID:PF12937, PF14252, PF00621

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:S-phase kinase-associated pro
Gene (Uniprot):SKP1
Chain IDs:C (auth: C1), D (auth: D1)
Chain Length:163
Number of Molecules:2
Biological Source:Homo sapiens

UniProt ID:P63208 Pfam ID:PF03931, PF01466

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Dynein light chain 1, cytopla
Gene (Uniprot):DYNLL1
Chain IDs:E (auth: E1), F (auth: F1)
Chain Length:89
Number of Molecules:2
Biological Source:Homo sapiens

UniProt ID:P63167 Pfam ID:PF01221

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Double zinc ribbon and ankyri
Gene (Uniprot):DZANK1
Chain IDs:G (auth: G1), H (auth: H1), I (auth: I1), J (auth: J1)
Chain Length:752
Number of Molecules:4
Biological Source:Homo sapiens

UniProt ID:Q9NVP4 Pfam ID:PF13287, PF12773, PF12796

Ligand Molecules

Primary Citation

In situ structure of the human ciliary transition zone links linker defects to primary ciliary dyskinesia

Zhou, H, Brown, A.Show

Science ? ? ? (2026)

DOI: 10.1126/science.aei5957

Primary Citation of related structures

Feedback Form