ISDA: 11OA

Deposition Date 2026-03-05

Release Date 2026-08-19

Last Version Date 2026-08-19

Entry Detail

PDB ID:

11OA

Keywords:

TRANSFERASE

Title:

Cryo-EM structure of human DNMT3A R882H octadecamer

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)

Expression System(s):

Escherichia coli bl21(de3)

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

5.04 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

Download Validation Report

Macromolecular Entities

Polymer Type:polypeptide(L)
Molecule:DNA (cytosine-5)-methyltransf
Mutagens:R882H
Chain IDs:A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R
Chain Length:633
Number of Molecules:18
Biological Source:Homo sapiens

Ligand Molecules

SAH

Primary Citation

Cryo-EM structure of human DNMT3A R882H octadecamer

Song, J, Lu, J, Chen, J.Show

To Be Published ? ? ? (?)

Primary Citation of related structures

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