ISDA: 11IE

Deposition Date 2026-02-25

Release Date 2026-09-02

Last Version Date 2026-09-02

Entry Detail

PDB ID:

11IE

Keywords:

MEMBRANE PROTEIN

Title:

2-APB bound rat TRPV2, H651S/D654T/N655D

Biological Source:

Source Organism(s):

Rattus norvegicus (Taxon ID: 10116)

Expression System(s):

Saccharomyces cerevisiae

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

3.07 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

Download Validation Report

Macromolecular Entities

Polymer Type:polypeptide(L)
Molecule:Transient receptor potential
Chain IDs:A, B, C, D
Chain Length:770
Number of Molecules:4
Biological Source:Rattus norvegicus

Ligand Molecules

FZ4

PEX

Primary Citation

Structural origins of species-specific differences in TRPV2 activation.

Fricke, T.C, Pumroy, R.A, Rocereta, J.A, De Jesus-Perez, J.J, Oprita, G, Meyer, M.J.A, Herzog, C, Echtermeyer, F.G, Hill, K, Leffler, A, Moiseenkova-Bell, V.Y.Show

Nat Commun 17 ? ? (2026)

PMID: 42624855 DOI: 10.1038/s41467-026-76831-7

Primary Citation of related structures

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