ISDA: 11FA

Deposition Date 2026-02-20

Release Date 2026-11-04

Last Version Date 2026-11-04

Entry Detail

PDB ID:

11FA

Keywords:

LYASE

Title:

Crystal structure of human Malonyl-CoA Decarboxylase

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)

Expression System(s):

Escherichia coli 'bl21-gold(de3)plyss ag'

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

3.25 Å

R-Value Free:

0.30

R-Value Work:

0.25

R-Value Observed:

0.25

Space Group:

C 2 2 21

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Macromolecular Entities

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Malonyl-CoA decarboxylase, mi
Gene (Uniprot):MLYCD
Mutagens:E19A, K20A, E239A, E240A, K241A
Chain IDs:A, B
Chain Length:460
Number of Molecules:2
Biological Source:Homo sapiens

UniProt ID:O95822 EC:4.1.1.9

Ligand Molecules

Primary Citation

Indacaterol Restores Metabolic Flexibility in Obesity

Ewida, H.A, Zoubi, S, Aziz, M.T, Bassani, T.B, Meneghello, R, Patel, D, Redrovan, D, Patra, S, Tareq, S, Korsapati, Y, Kallem, R.R, Szweda, P, Szweda, L, Bickel, U, Cardoso, A.C, Chelikani, P.K, Ahmed, M.S.Show

To Be Published ? ? ? (?)

Primary Citation of related structures

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