ISDA: 10YH

Deposition Date 2026-02-12

Release Date 2026-03-18

Last Version Date 2026-03-18

Entry Detail

PDB ID:

10YH

Keywords:

DNA BINDING PROTEIN/DNA

Title:

DNA Ligase IIIa bound to a nucleosome containing a nick at SHL-6 (composite)

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)
synthetic construct (Taxon ID: 32630)

Expression System(s):

Escherichia coli

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

2.90 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

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Macromolecular Entities

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Histone H3.2
Gene (Uniprot):H3C15, H3C14, H3C13
Chain IDs:A, E
Chain Length:97
Number of Molecules:2
Biological Source:Homo sapiens

UniProt ID:Q71DI3 Pfam ID:PF00125

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Histone H4
Gene (Uniprot):H4C1, H4C2, H4C3, H4C4, H4C5, H4C6, H4C8, H4C9, H4C11, H4C12, H4C13, H4C14, H4C15, H4C16
Chain IDs:B, F
Chain Length:80
Number of Molecules:2
Biological Source:Homo sapiens

UniProt ID:P62805 Pfam ID:PF15511

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Histone H2A type 1-H
Gene (Uniprot):H2AC12
Chain IDs:C, G
Chain Length:107
Number of Molecules:2
Biological Source:Homo sapiens

UniProt ID:Q96KK5 Pfam ID:PF00125, PF16211

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Histone H2B type 1-M
Gene (Uniprot):H2BC14
Chain IDs:D, H
Chain Length:93
Number of Molecules:2
Biological Source:Homo sapiens

UniProt ID:Q99879 Pfam ID:PF00125

Polymer Type:polydeoxyribonucleotide
Molecule:601 I strand (non-damaged str
Chain IDs:I
Chain Length:147
Number of Molecules:1
Biological Source:synthetic construct

Polymer Type:polydeoxyribonucleotide
Molecule:601 J strand (damaged strand
Chain IDs:J
Chain Length:15
Number of Molecules:1
Biological Source:synthetic construct

Polymer Type:polydeoxyribonucleotide
Molecule:601 K strand (damaged strand
Chain IDs:K
Chain Length:132
Number of Molecules:1
Biological Source:synthetic construct

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:DNA ligase 3
Gene (Uniprot):LIG3
Chain IDs:L
Chain Length:208
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:P49916 Pfam ID:PF01068 EC:6.5.1.1

Ligand Molecules

AMP

Primary Citation

DNA Ligase IIIa bound to a nucleosome containing a nick at SHL-6

Boesch, D.J, Weaver, T.M.Show

To Be Published ? ? ? (?)

Primary Citation of related structures

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