Search Count: 10
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Crystal Structure Of The First Bromodomain Of Human Brd4 In Complex With Bmt-206059 Aka 2-{(3M)-3-(1,4-Dimethyl-1H-1,2,3-Triazol-5-Yl)-8-Fluoro-5-[(S)-(Oxan-4-Yl)(Phenyl)Methyl]-5H-Pyrido[3,2-B]Indol-7-Yl}Propan-2-Ol, Triply Deuterated On The 4-Methyl Group
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.69 Å Release Date: 2022-08-17 Classification: CELL CYCLE Ligands: PQF, NA, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2022-08-17
Ligands: PQF, NA, EDO
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Crystal Structure Of The First Bromodomain Of Human Brd4 In Complex With 2-{(7P)-7-(1,4-Dimethyl-1H-1,2,3-Triazol-5-Yl)-8-Fluoro-5-[(S)-(Oxan-4-Yl)(Phenyl)Methyl]-5H-Pyrido[3,2-B]Indol-3-Yl}Propan-2-Ol
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.76 Å Release Date: 2021-09-29 Classification: CELL CYCLE Ligands: YWY |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2021-09-29
Ligands: YWY
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Crystal Structure Of The First Bromodomain Of Human Brd4 In Complex With 2-{3-(1,4-Dimethyl-1H-1,2,3-Triazol-5-Yl)-6-Fluoro-5-[(S)-(3-Fluoropyridin-2-Yl)(Oxan-4-Yl)Methyl]-5H-Pyrido[3,2-B]Indol-7-Yl}Propan-2-Ol
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.19 Å Release Date: 2021-05-26 Classification: CELL CYCLE Ligands: YX4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2021-05-26
Ligands: YX4
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Discovery Of Bms-986144, A Third Generation, Pan Genotype Ns3/4A Protease Inhibitor For The Treatment Of Hepatitis C Virus Infection
Organism: Hepacivirus c
Method: X-RAY DIFFRACTION Resolution:2.15 Å Release Date: 2020-12-16 Classification: VIRAL PROTEIN Ligands: ZN, GXO |
Organism: Hepacivirus c
Method: X-RAY DIFFRACTION
Release Date: 2020-12-16
Ligands: ZN, GXO
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Structure Of Human Pregnane X Receptor Ligand Binding Domain Bound Tethered With Src Co-Activator Peptide In Complex With (S,S)-1
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.27 Å Release Date: 2020-09-23 Classification: NUCLEAR PROTEIN Ligands: QCG, GOL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-09-23
Ligands: QCG, GOL
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Crystal Structure Of The Hepatitis C Virus Genotype 2A Strain Jfh1 L30S Ns5B Rna-Dependent Rna Polymerase In Complex With 5-[3-(Tert-Butylcarbamoyl)Phenyl]-6-(Ethylamino)-2-(4-Fluorophenyl)-N-Methylfuro[2,3-B]Pyridine-3-Carboxamide
Organism: Hepatitis c virus genotype 2a (isolate jfh-1)
Method: X-RAY DIFFRACTION Resolution:1.97 Å Release Date: 2017-03-15 Classification: TRANSFERASE/TRANSFERASE inhibitor Ligands: 7NG, SO4, PE5, PG4 |
Organism: Hepatitis c virus genotype 2a (isolate jfh-1)
Method: X-RAY DIFFRACTION
Release Date: 2017-03-15
Ligands: 7NG, SO4, PE5, PG4
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Crystal Structure Of The Hepatitis C Virus Ns5B Rna- Dependent Rna Polymerase In Complex With 5-[3-(Tert-Butylcarbamoyl)Phenyl]-6-(Ethylamino)-2-(4-Fluorophenyl)-N-Methylfuro[2,3-B]Pyridine-3-Carboxamide
Organism: Hepatitis c virus genotype 1b (isolate con1)
Method: X-RAY DIFFRACTION Resolution:3.04 Å Release Date: 2017-03-15 Classification: TRANSFERASE/TRANSFERASE inhibitor Ligands: 23E, SO4, 7NG |
Organism: Hepatitis c virus genotype 1b (isolate con1)
Method: X-RAY DIFFRACTION
Release Date: 2017-03-15
Ligands: 23E, SO4, 7NG
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Crystal Structure Of Hepatis C Virus Protease (Ns3) Complexed With Bms-605339 Aka N-(Tert-Butoxycarbonyl)-3-Me Thyl-L-Valyl-(4R)-N-((1R,2S)-1-((Cyclopropylsulfonyl)Carba Moyl)-2-Vinylcyclopropyl)-4-((6-Methoxy-1-Isoquinolinyl)Ox Y)-L-Prolinamide
Organism: Hepatitis c virus
Method: X-RAY DIFFRACTION Resolution:1.62 Å Release Date: 2014-03-26 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: 2R8, ZN, SO4, GOL |
Organism: Hepatitis c virus
Method: X-RAY DIFFRACTION
Release Date: 2014-03-26
Ligands: 2R8, ZN, SO4, GOL
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Crystal Structure Of Hepatis C Virus Protease (Ns3) Complexed With Bms-650032 Aka N-(Tert-Butoxycarbonyl)-3-Me Thyl-L-Valyl-(4R)-4-((7-Chloro-4-Methoxy-1-Isoquinolinyl)O Xy)-N-((1R,2S)-1-((Cyclopropylsulfonyl)Carbamoyl)-2-Vinylc Yclopropyl)-L-Prolinamide
Organism: Hepatitis c virus
Method: X-RAY DIFFRACTION Resolution:2.20 Å Release Date: 2014-03-26 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: 2R9, ZN |
Organism: Hepatitis c virus
Method: X-RAY DIFFRACTION
Release Date: 2014-03-26
Ligands: 2R9, ZN
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Crystal Structure Of 11B-Hsd1 Double Mutant (L262R, F278E) Complexed With 8-{[(2-Cyanopyridin-3-Yl)Methyl]Sulfanyl}-6-Hydroxy-3,4-Dihydro-1H-Pyrano[3,4-C]Pyridine-5-Carbonitrile
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.80 Å Release Date: 2011-11-02 Classification: Oxidoreductase/Oxidoreductase Inhibitor Ligands: NAP, 07M, GOL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2011-11-02
Ligands: NAP, 07M, GOL