Search Count: 25
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Structure Of Cbl-B Bound To Compound 8
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.77 Å Release Date: 2026-07-01 Classification: LIGASE/INHIBITOR Ligands: GOL, ZN, EDO, MG, A1DCC |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2026-07-01
Ligands: GOL, ZN, EDO, MG, A1DCC
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Structure Of Sarm1 Tir Domain Bound To G8758
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.10 Å Release Date: 2026-02-04 Classification: LYASE Ligands: A1BTS |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2026-02-04
Ligands: A1BTS
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Structure Of Sarm1 Tir Domain Bound To G6831
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.75 Å Release Date: 2026-02-04 Classification: LYASE Ligands: A1BU7 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2026-02-04
Ligands: A1BU7
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Structure Of Sarm1 Tir Domain Bound To G2756
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.93 Å Release Date: 2026-02-04 Classification: LYASE Ligands: A1BTR |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2026-02-04
Ligands: A1BTR
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Crebbp Bromodomain In Complex With Cpd3 ((S)-1-(3-(6-(1-Methyl-1H-Pyrazol-4-Yl)-3,4-Dihydroquinolin-1(2H)-Yl)-1-(Tetrahydrofuran-3-Yl)-1,4,6,7-Tetrahydro-5H-Pyrazolo[4,3-C]Pyridin-5-Yl)Ethan-1-One)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.60 Å Release Date: 2018-03-07 Classification: TRANSCRIPTION REGULATOR/INHIBITOR Ligands: 9U7 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2018-03-07
Ligands: 9U7
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Crebbp Bromodomain In Complex With Cpd8 (1-(3-(7-(Difluoromethyl)-6-(1-Methyl-1H-Pyrazol-4-Yl)-3,4-Dihydroquinolin-1(2H)-Yl)-1-(Tetrahydrofuran-3-Yl)-1,4,6,7-Tetrahydro-5H-Pyrazolo[4,3-C]Pyridin-5-Yl)Ethan-1-One)
Organism: Mus musculus
Method: X-RAY DIFFRACTION Resolution:1.43 Å Release Date: 2018-03-07 Classification: TRANSFERASE/INHIBITOR Ligands: 9UA, DMS, GOL |
Organism: Mus musculus
Method: X-RAY DIFFRACTION
Release Date: 2018-03-07
Ligands: 9UA, DMS, GOL
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Crebbp Bromodomain In Complex With Cpd10 (1-(3-(7-(Difluoromethyl)-6-(1-Methyl-1H-Pyrazol-4-Yl)-3,4-Dihydroquinolin-1(2H)-Yl)-1-(Tetrahydro-2H-Pyran-4-Yl)-1,4,6,7-Tetrahydro-5H-Pyrazolo[4,3-C]Pyridin-5-Yl)Ethan-1-One)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.55 Å Release Date: 2018-03-07 Classification: TRANSCRIPTION REGULATOR/INHIBITOR Ligands: 9UD |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2018-03-07
Ligands: 9UD
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Crebbp Bromodomain In Complex With Cpd17 (N,2,7-Trimethyl-2,3-Dihydro-4H-Benzo[B][1,4]Oxazine-4-Carboxamide)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.70 Å Release Date: 2018-03-07 Classification: TRANSCRIPTION REGULATOR/INHIBITOR Ligands: SO4, 9UG |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2018-03-07
Ligands: SO4, 9UG
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Jak2 Kinase (Jh1 Domain) In Complex With Tg101209
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.40 Å Release Date: 2013-08-07 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 1M3 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-08-07
Ligands: 1M3
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Jak2 Kinase (Jh1 Domain) In Complex With Compound 9
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.85 Å Release Date: 2013-08-07 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 1K3, GOL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-08-07
Ligands: 1K3, GOL
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Tyk2 (Jh1) In Complex With 2,6-Dichloro-4-Cyano-N-{2-[(Cyclopropylcarbonyl)Amino]Pyridin-4-Yl}Benzamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.31 Å Release Date: 2013-05-29 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 0X6 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-05-29
Ligands: 0X6
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Tyk2 (Jh1) In Complex With 2,6-Dichloro-N-[2-({[(1R,2R)-2-Fluorocyclopropyl]Carbonyl}Amino)Pyridin-4-Yl]Benzamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.40 Å Release Date: 2013-05-29 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 0XH |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-05-29
Ligands: 0XH
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Tyk2 (Jh1) In Complex With 2,6-Dichloro-4-Cyano-N-[2-({[(1R,2R)-2-Fluorocyclopropyl]Carbonyl}Amino)Pyridin-4-Yl]Benzamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.50 Å Release Date: 2013-05-29 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 0XP |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-05-29
Ligands: 0XP
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Discovery Of Gdc-0980: A Potent, Selective, And Orally Available Class I Phosphatidylinositol 3-Kinase (Pi3K)/Mammalian Target Of Rapamycin (Mtor) Kinase Inhibitor For The Treatment Of Cancer
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.79 Å Release Date: 2011-11-02 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 980 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2011-11-02
Ligands: 980
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Structure-Based Design Of Thienobenzoxepin Inhibitors Of Pi3- Kinase
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.50 Å Release Date: 2011-08-03 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: FAV |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2011-08-03
Ligands: FAV
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Structure-Based Design Of Thienobenzoxepin Inhibitors Of Pi3-Kinase
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.90 Å Release Date: 2011-08-03 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: FAZ |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2011-08-03
Ligands: FAZ
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Structure-Based Optimization Of Pyrazolo -Pyrimidine And -Pyridine Inhibitors Of Pi3-Kinase
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.75 Å Release Date: 2010-12-29 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: NZS |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2010-12-29
Ligands: NZS
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Structure-Based Optimization Of Pyrazolo -Pyrimidine And -Pyridine Inhibitors Of Pi3-Kinase
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.60 Å Release Date: 2010-12-29 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: NZU |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2010-12-29
Ligands: NZU
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Crystal Structures Of Pan-Pi3-Kinase And Dual Pan-Pi3-Kinase/Mtor Inhibitors
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:3.00 Å Release Date: 2010-02-16 Classification: TRANSFERASE Ligands: JZW |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2010-02-16
Ligands: JZW
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Discovery Of (Thienopyrimidin-2-Yl)Aminopyrimidines As Potent, Selective, And Orally Available Pan-Pi3-Kinase And Dual Pan-Pi3-Kinase/Mtor Inhibitors For The Treatment Of Cancer
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.90 Å Release Date: 2010-02-16 Classification: TRANSFERASE Ligands: JZX |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2010-02-16
Ligands: JZX