Search Count: 39
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Btk Fluorocyclopropyl Amide Inhibitor, Compound 25
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.60 Å Release Date: 2020-07-22 Classification: TRANSFERASE/TRANSFERASE Inhibitor Ligands: V1G, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-07-22
Ligands: V1G, SO4
 |
Bruton'S Tyrosine Kinase (Btk) With Gdc-0853
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.59 Å Release Date: 2018-02-28 Classification: Transferase/Transferase Inhibitor Ligands: 9AJ, EDO, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2018-02-28
Ligands: 9AJ, EDO, SO4
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Bruton'S Tyrosine Kinase (Btk) With Compound G-744
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.62 Å Release Date: 2017-07-05 Classification: Transferase/Transferase Inhibitor Ligands: SO4, GOL, PG0, 9B1 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-07-05
Ligands: SO4, GOL, PG0, 9B1
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Bruton'S Tyrosine Kinase (Btk) With Pyridazinone Compound 9
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.39 Å Release Date: 2016-09-14 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: SO4, GOL, PG0, 6XL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-09-14
Ligands: SO4, GOL, PG0, 6XL
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Bruton'S Tyrosine Kinase (Btk) With Pyridazinone Compound 23
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.36 Å Release Date: 2015-12-02 Classification: TRANSFERASE Ligands: SO4, GOL, PG0, 3YO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-12-02
Ligands: SO4, GOL, PG0, 3YO
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Crystal Structure Of The Kinase Domain Of Bruton'S Tyrosine Kinase With Gdc0834
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.95 Å Release Date: 2015-01-28 Classification: transferase/transferase inhibitor Ligands: SO4, 2VL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-01-28
Ligands: SO4, 2VL
 |
3-Heterocyclyl Quinolone Bound To Hcv Ns5B
Organism: Hepatitis c virus subtype 1b
Method: X-RAY DIFFRACTION Resolution:2.17 Å Release Date: 2011-12-21 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: KLI |
Organism: Hepatitis c virus subtype 1b
Method: X-RAY DIFFRACTION
Release Date: 2011-12-21
Ligands: KLI
 |
Human B-Raf Kinase Domain In Complex With An Bromopyridine Benzamide Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:3.40 Å Release Date: 2011-10-05 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: TV4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2011-10-05
Ligands: TV4
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Human B-Raf Kinase Domain In Complex With A Methoxypyrazolopyridinyl Benzamide Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:3.30 Å Release Date: 2011-10-05 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: B0R |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2011-10-05
Ligands: B0R
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Hcv Ns5B With A Bound Quinolone Inhibitor
Organism: Hepatitis c virus
Method: X-RAY DIFFRACTION Resolution:2.20 Å Release Date: 2010-11-17 Classification: Transferase/Transferase Inhibitor Ligands: C9A |
Organism: Hepatitis c virus
Method: X-RAY DIFFRACTION
Release Date: 2010-11-17
Ligands: C9A
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Crystal Structure Of The Human Btk Kinase Domain
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.30 Å Release Date: 2010-11-03 Classification: TRANSFERASE |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2010-11-03
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Novel 5-Azaindole Factor Viia Inhibitors
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.35 Å Release Date: 2007-01-23 Classification: HYDROLASE/BLOOD CLOTTING Ligands: 7NH |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2007-01-23
Ligands: 7NH
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Discovery Of A Novel Hydroxy Pyrazole Based Factor Ixa Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.95 Å Release Date: 2006-04-04 Classification: HYDROLASE/BLOOD CLOTTING Ligands: 6NH |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2006-04-04
Ligands: 6NH
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Discovery Of Novel Heterocyclic Factor Viia Inhibitors
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.54 Å Release Date: 2006-02-28 Classification: HYDROLASE/BLOOD CLOTTING Ligands: N1H |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2006-02-28
Ligands: N1H
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Factor Viia Inhibitors: Chemical Optimization, Preclinical Pharmacokinetics, Pharmacodynamics, And Efficacy In A Baboon Thrombosis Model
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.24 Å Release Date: 2006-02-14 Classification: BLOOD CLOTTING Ligands: C1B |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2006-02-14
Ligands: C1B
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Expression, Crystallization And Three-Dimensional Structure Of The Catalytic Domain Of Human Plasma Kallikrein: Implications For Structure-Based Design Of Protease Inhibitors
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.85 Å Release Date: 2005-10-11 Classification: BLOOD CLOTTING, HYDROLASE Ligands: BEN |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2005-10-11
Ligands: BEN
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Expression, Crystallization And The Three-Dimensional Structure Of The Catalytic Domain Of Human Plasma Kallikrein: Implications For Structure-Based Design Of Protease Inhibitors
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.40 Å Release Date: 2005-10-11 Classification: BLOOD CLOTTING, HYDROLASE Ligands: PO4, BEN |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2005-10-11
Ligands: PO4, BEN
 |
Dissecting And Designing Inhibitor Selectivity Determinants At The S1 Site Using An Artificial Ala190 Protease (Ala190 Upa)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.68 Å Release Date: 2004-09-21 Classification: BLOOD CLOTTING, hydrolase Ligands: 696, CIT |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2004-09-21
Ligands: 696, CIT
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Dissecting And Designing Inhibitor Selectivity Determinants At The S1 Site Using An Artificial Ala190 Protease (Ala190 Upa)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.85 Å Release Date: 2004-09-21 Classification: BLOOD CLOTTING, hydrolase Ligands: ESI, CIT |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2004-09-21
Ligands: ESI, CIT
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Dissecting And Designing Inhibitor Selectivity Determinants At The S1 Site Using An Artificial Ala190 Protease (Ala190 Upa)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.63 Å Release Date: 2004-09-21 Classification: BLOOD CLOTTING, hydrolase Ligands: CR9, CIT |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2004-09-21
Ligands: CR9, CIT