Search Count: 35
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Crystal Structure Of His-Tagged Human Thymidylate Synthase (Ht-Hts) In Complex With Fdump And Raltitrexed (Tomudex)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.60 Å Release Date: 2021-05-19 Classification: TRANSFERASE Ligands: D16, UFP, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2021-05-19
Ligands: D16, UFP, EDO
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Crystal Structure Of Ts-Dhfr From Cryptosporidium Hominis In Complex With Nadph, Fdump And 2-(2-(4-((2-Amino-4-Oxo-4,7-Dihydro-3H-Pyrrolo[2,3-D]Pyrimidin-5-Yl)Methyl)Benzamido)-4-Methoxyphenyl)Acetic Acid
Organism: Cryptosporidium hominis
Method: X-RAY DIFFRACTION Resolution:2.69 Å Release Date: 2019-10-16 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: NDP, UFP, OED, MTX |
Organism: Cryptosporidium hominis
Method: X-RAY DIFFRACTION
Release Date: 2019-10-16
Ligands: NDP, UFP, OED, MTX
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Crystal Structure Of Ts-Dhfr From Cryptosporidium Hominis In Complex With Nadph, Fdump And 2-(4-((2-Amino-4-Oxo-4,7-Dihydro-3H-Pyrrolo[2,3-D]Pyrimidin-5-Yl)Methyl)Benzamido)Benzoic Acid
Organism: Cryptosporidium hominis
Method: X-RAY DIFFRACTION Resolution:2.80 Å Release Date: 2019-10-02 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: NDP, UFP, OG7, MTX, SO4 |
Organism: Cryptosporidium hominis
Method: X-RAY DIFFRACTION
Release Date: 2019-10-02
Ligands: NDP, UFP, OG7, MTX, SO4
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Crystal Structure Of Ts-Dhfr From Cryptosporidium Hominis In Complex With Nadph, Fdump And 2-(4-((2-Amino-4-Oxo-4,7-Dihydro-3H-Pyrrolo[2,3-D]Pyrimidin-5-Yl)Methyl)Benzamido)-4-Chlorobenzoic Acid
Organism: Cryptosporidium hominis
Method: X-RAY DIFFRACTION Resolution:2.53 Å Release Date: 2019-10-02 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: NDP, UFP, OE7, MTX |
Organism: Cryptosporidium hominis
Method: X-RAY DIFFRACTION
Release Date: 2019-10-02
Ligands: NDP, UFP, OE7, MTX
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Crystal Structure Of Ts-Dhfr From Cryptosporidium Hominis In Complex With Nadph, Fdump And 2-(2-(4-((2-Amino-4-Oxo-4,7-Dihydro-3H-Pyrrolo[2,3-D]Pyrimidin-5-Yl)Methyl)Benzamido)Phenyl)Acetic Acid.
Organism: Cryptosporidium hominis
Method: X-RAY DIFFRACTION Resolution:2.89 Å Release Date: 2019-10-02 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: NDP, UFP, OF7, MTX, SO4 |
Organism: Cryptosporidium hominis
Method: X-RAY DIFFRACTION
Release Date: 2019-10-02
Ligands: NDP, UFP, OF7, MTX, SO4
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Crystal Structure Of Ts-Dhfr From Cryptosporidium Hominis In Complex With Nadph, Fdump And 2-((4-((2-Amino-4-Oxo-4,7-Dihydro-3H-Pyrrolo[2,3-D]Pyrimidin-5-Yl)Methyl)Benzamido)Methyl)Benzoic Acid.
Organism: Cryptosporidium hominis
Method: X-RAY DIFFRACTION Resolution:2.79 Å Release Date: 2019-10-02 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: NDP, UFP, OF4, MTX, SO4 |
Organism: Cryptosporidium hominis
Method: X-RAY DIFFRACTION
Release Date: 2019-10-02
Ligands: NDP, UFP, OF4, MTX, SO4
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Crystal Structure Of Ts-Dhfr From Cryptosporidium Hominis In Complex With Nadph, Fdump And 3-(2-(4-((2-Amino-4-Oxo-4,7-Dihydro-3H-Pyrrolo[2,3-D]Pyrimidin-5-Yl)Methyl)Benzamido)Phenyl)Propanoic Acid.
Organism: Cryptosporidium hominis
Method: X-RAY DIFFRACTION Resolution:3.09 Å Release Date: 2019-10-02 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: NDP, UFP, OG4, MTX |
Organism: Cryptosporidium hominis
Method: X-RAY DIFFRACTION
Release Date: 2019-10-02
Ligands: NDP, UFP, OG4, MTX
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Crystal Structure Of Ts-Dhfr From Cryptosporidium Hominis In Complex With Nadph, Fdump And 2-(4-((2-Amino-4-Oxo-4,7-Dihydro-3H-Pyrrolo[2,3-D]Pyrimidin-5-Yl)Methyl)Benzamido)Terephthalic Acid.
Organism: Cryptosporidium hominis
Method: X-RAY DIFFRACTION Resolution:3.32 Å Release Date: 2019-10-02 Classification: transferase/transferase inhibitor Ligands: NDP, UFP, OEJ, MTX |
Organism: Cryptosporidium hominis
Method: X-RAY DIFFRACTION
Release Date: 2019-10-02
Ligands: NDP, UFP, OEJ, MTX
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Crystal Structure Of Ts-Dhfr From Cryptosporidium Hominis In Complex With Nadph, Fdump And 2-(4-((2-Amino-4-Oxo-4,7-Dihydro-3H-Pyrrolo[2,3-D]Pyrimidin-5-Yl)Methyl)Benzamido)-4-Methoxybenzoic Acid.
Organism: Cryptosporidium hominis
Method: X-RAY DIFFRACTION Resolution:2.81 Å Release Date: 2019-10-02 Classification: transferase/transferase inhibitor Ligands: NDP, UFP, OEA, MTX |
Organism: Cryptosporidium hominis
Method: X-RAY DIFFRACTION
Release Date: 2019-10-02
Ligands: NDP, UFP, OEA, MTX
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Crystal Structure Of Ts-Dhfr From Cryptosporidium Hominis In Complex With Nadph, Fdump And 2-(4-((2-Amino-4-Oxo-4,7-Dihydro-3H-Pyrrolo[2,3-D]Pyrimidin-5-Yl)Methyl)Benzamido)-4-Cyanobenzoic Acid.
Organism: Cryptosporidium hominis
Method: X-RAY DIFFRACTION Resolution:2.98 Å Release Date: 2019-10-02 Classification: transferase/transferase inhibitor Ligands: NDP, UFP, OG1, MTX, SO4 |
Organism: Cryptosporidium hominis
Method: X-RAY DIFFRACTION
Release Date: 2019-10-02
Ligands: NDP, UFP, OG1, MTX, SO4
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Crystal Structure Of Ts-Dhfr From Cryptosporidium Hominis In Complex With Nadph, Fdump And 2-(4-((2-Amino-4-Oxo-4,7-Dihydro-3H-Pyrrolo[2,3-D]Pyrimidin-5-Yl)Methyl)Benzamido)-4-Carbamoylbenzoic Acid.
Organism: Cryptosporidium hominis
Method: X-RAY DIFFRACTION Resolution:2.71 Å Release Date: 2019-10-02 Classification: transferase/transferase inhbitor Ligands: NDP, UFP, OFJ, MTX, SO4 |
Organism: Cryptosporidium hominis
Method: X-RAY DIFFRACTION
Release Date: 2019-10-02
Ligands: NDP, UFP, OFJ, MTX, SO4
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Crystal Structure Of Ts-Dhfr From Cryptosporidium Hominis In Complex With Nadph, Fdump And 2-(2-(4-((2-Amino-4-Oxo-4,7-Dihydro-3H-Pyrrolo[2,3-D]Pyrimidin-5-Yl)Methyl)Benzamido)-4-Cyanophenyl)Acetic Acid.
Organism: Cryptosporidium hominis
Method: X-RAY DIFFRACTION Resolution:2.94 Å Release Date: 2019-10-02 Classification: transferase/transferase inhibitor Ligands: NDP, UFP, OFD, MTX |
Organism: Cryptosporidium hominis
Method: X-RAY DIFFRACTION
Release Date: 2019-10-02
Ligands: NDP, UFP, OFD, MTX
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Crystal Structure Of Ts-Dhfr From Cryptosporidium Hominis In Complex With Nadph, Fdump And 3-(4-((2-Amino-4-Oxo-4,7-Dihydro-3H-Pyrrolo[2,3-D]Pyrimidin-5-Yl)Methyl)Benzamido)-4-(Carboxymethyl)Benzoic Acid.
Organism: Cryptosporidium hominis
Method: X-RAY DIFFRACTION Resolution:2.89 Å Release Date: 2019-10-02 Classification: transferase/transferase inhibitor Ligands: NDP, UFP, OEP, MTX |
Organism: Cryptosporidium hominis
Method: X-RAY DIFFRACTION
Release Date: 2019-10-02
Ligands: NDP, UFP, OEP, MTX
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Crystal Structure Of Ts-Dhfr From Cryptosporidium Hominis In Complex With Nadph, Fdump, Mtx And 2-Amino-4-Oxo-4,7-Dihydro-Pyrrolo[2,3-D]Pyrimidine-Methyl-Phenyl-D-Glutamic Acid
Organism: Cryptosporidium hominis
Method: X-RAY DIFFRACTION Resolution:3.21 Å Release Date: 2019-06-19 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: NDP, UFP, D96, MTX |
Organism: Cryptosporidium hominis
Method: X-RAY DIFFRACTION
Release Date: 2019-06-19
Ligands: NDP, UFP, D96, MTX
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Crystal Structure Of His-Tag Human Thymidylate Synthase (Ht-Hts) In Complex With Fdump
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.08 Å Release Date: 2019-04-10 Classification: TRANSFERASE Ligands: UFP, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2019-04-10
Ligands: UFP, SO4
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Crystal Structure Of Enteroccocus Faecalis Thymidylate Synthase (Efts) In Complex With Fdump
Organism: Enterococcus faecalis (strain atcc 700802 / v583), Enterococcus faecalis
Method: X-RAY DIFFRACTION Resolution:2.88 Å Release Date: 2019-04-10 Classification: TRANSFERASE Ligands: UFP, SO4, FFO |
Organism: Enterococcus faecalis (strain atcc 700802 / v583), Enterococcus faecalis
Method: X-RAY DIFFRACTION
Release Date: 2019-04-10
Ligands: UFP, SO4, FFO
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Mouse Thymidylate Synthase In Ternary Complex With Fdump And Methylenetetrahydrofolate.
Organism: Mus musculus
Method: X-RAY DIFFRACTION Resolution:1.55 Å Release Date: 2016-10-26 Classification: TRANSFERASE Ligands: UFP, C2F |
Organism: Mus musculus
Method: X-RAY DIFFRACTION
Release Date: 2016-10-26
Ligands: UFP, C2F
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Crystal Structure Of Ts-Dhfr From Cryptosporidium Hominis In Complex With Nadph, Fdump, Methotrexate And 2-Amino-4-Oxo-4,7-Dihydro-Pyrrolo[2,3-D]Pyrimidine-Methyl-Phenyl-L-Glutamic Acid.
Organism: Cryptosporidium hominis
Method: X-RAY DIFFRACTION Resolution:3.45 Å Release Date: 2014-10-15 Classification: transferase/transferase inhibitor Ligands: NDP, UFP, 2XB, MTX |
Organism: Cryptosporidium hominis
Method: X-RAY DIFFRACTION
Release Date: 2014-10-15
Ligands: NDP, UFP, 2XB, MTX
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Crystal Structure Of Ts-Dhfr From Cryptosporidium Hominis In Complex With Nadph, Fdump And 2-Amino-4-Oxo-4,7-Dihydro-Pyrrolo[2,3-D]Pyrimidine-Methyl-Phenyl-L-Glutamic Acid.
Organism: Cryptosporidium hominis
Method: X-RAY DIFFRACTION Resolution:2.78 Å Release Date: 2014-10-15 Classification: transferase/transferase inhibitor Ligands: NDP, UFP, 2XB |
Organism: Cryptosporidium hominis
Method: X-RAY DIFFRACTION
Release Date: 2014-10-15
Ligands: NDP, UFP, 2XB
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Crystal Structure Of Ts-Dhfr From Cryptosporidium Hominis In Complex With Nadph, Methotrexate, Fdump And 4-((2-Amino-6-Methyl-4-Oxo-4,7-Dihydro-3H-Pyrrolo[2,3-D]Pyrimidin-5-Yl)Thio)-2-Chlorophenyl)-L-Glutamic Acid
Organism: Cryptosporidium hominis
Method: X-RAY DIFFRACTION Resolution:3.08 Å Release Date: 2013-08-21 Classification: TRANSFERASE,OXIDOREDUCTASE/INHIBITOR Ligands: NDP, UFP, MTX, 1UF |
Organism: Cryptosporidium hominis
Method: X-RAY DIFFRACTION
Release Date: 2013-08-21
Ligands: NDP, UFP, MTX, 1UF