Search Count: 44
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Cdk2/Cycline Bound To Compound 11 With P-Loop In The Ee And Cc Conformations
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.12 Å Release Date: 2025-04-30 Classification: CELL CYCLE Ligands: A1CAE |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-04-30
Ligands: A1CAE
 |
Cdk2/Cycline Bound To Compound 16 With P-Loop In The Ee Conformation
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.98 Å Release Date: 2025-04-30 Classification: CELL CYCLE Ligands: A1CAH |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-04-30
Ligands: A1CAH
 |
Cdk2/Cycline Bound To Compound 19 With P-Loop In The Ee And Ec Conformations
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.95 Å Release Date: 2025-04-30 Classification: CELL CYCLE Ligands: A1CAF |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-04-30
Ligands: A1CAF
 |
Cdk2/Cycline Bound To Compound 20 With P-Loop In The Ee And Cc Conformations
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.10 Å Release Date: 2025-04-30 Classification: CELL CYCLE Ligands: A1CAG |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-04-30
Ligands: A1CAG
 |
Cdk2/Cycline Bound To Compound 21 With P-Loop In The Ee And Cc Conformations
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.00 Å Release Date: 2025-04-30 Classification: CELL CYCLE Ligands: A1CAI |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-04-30
Ligands: A1CAI
 |
Fgfr2 Kinase Domain Bound To Reversible Inhibitor Cmpd 3
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.24 Å Release Date: 2024-02-14 Classification: ONCOPROTEIN Ligands: GOL, GSH, WXQ |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-02-14
Ligands: GOL, GSH, WXQ
 |
Fgfr2 Kinase Domain Bound To Irreversible Inhibitor Cmpd 10
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:3.33 Å Release Date: 2024-02-14 Classification: Transferase/Inhibitor Ligands: GOL, UIM, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-02-14
Ligands: GOL, UIM, SO4
 |
Identification Of Gdc-1971 (Rly-1971), A Shp2 Inhibitor Designed For The Treatment Of Solid Tumors
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.40 Å Release Date: 2023-10-11 Classification: HYDROLASE Ligands: SO4, YR2 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2023-10-11
Ligands: SO4, YR2
 |
Identification Of Gdc-1971 (Rly-1971), A Shp2 Inhibitor Designed For The Treatment Of Solid Tumors
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.84 Å Release Date: 2023-10-11 Classification: HYDROLASE Ligands: SO4, YT2 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2023-10-11
Ligands: SO4, YT2
 |
Identification Of Gdc-1971 (Rly-1971), A Shp2 Inhibitor Designed For The Treatment Of Solid Tumors
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.10 Å Release Date: 2023-10-11 Classification: HYDROLASE Ligands: ZH5 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2023-10-11
Ligands: ZH5
 |
Identification Of Gdc-1971 (Rly-1971), A Shp2 Inhibitor Designed For The Treatment Of Solid Tumors
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.27 Å Release Date: 2023-10-11 Classification: HYDROLASE/INHIBITOR Ligands: ZJX |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2023-10-11
Ligands: ZJX
 |
Discovery And Clinical Validation Of Rly-4008, The First Highly Selective Fgfr2 Inhibitor With Activity Across Fgfr2 Alterations And Resistance Mutations
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:3.79 Å Release Date: 2023-06-07 Classification: TRANSFERASE/INHIBITOR Ligands: WCJ |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2023-06-07
Ligands: WCJ
 |
G-925 Bound To The Smarca4 (Brg1) Bromodomain
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.16 Å Release Date: 2022-08-17 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: GGU |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2022-08-17
Ligands: GGU
 |
G-059 Bound To The Smarca4 (Brg1) Bromodomain
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.61 Å Release Date: 2022-08-17 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: GJN |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2022-08-17
Ligands: GJN
 |
Taf1-Bd2 In Complex With Cpd27 (6-(But-3-En-1-Yl)-4-(1-Methyl-6-(Morpholine-4-Carbonyl)-1H-Benzo[D]Imidazol-4-Yl)-1,6-Dihydro-7H-Pyrrolo[2,3-C]Pyridin-7-One)
Organism: Oryctolagus cuniculus
Method: X-RAY DIFFRACTION Resolution:2.00 Å Release Date: 2018-11-14 Classification: Transcription/Inhibitor Ligands: G9V |
Organism: Oryctolagus cuniculus
Method: X-RAY DIFFRACTION
Release Date: 2018-11-14
Ligands: G9V
 |
Taf1-Bd2 In Complex With Cpd8 (6-(But-3-En-1-Yl)-4-(3-(Morpholine-4-Carbonyl)Phenyl)-1,6-Dihydro-7H-Pyrrolo[2,3-C]Pyridin-7-One)
Organism: Oryctolagus cuniculus
Method: X-RAY DIFFRACTION Resolution:1.30 Å Release Date: 2018-10-31 Classification: Transcription/Inhibitor Ligands: G9Y |
Organism: Oryctolagus cuniculus
Method: X-RAY DIFFRACTION
Release Date: 2018-10-31
Ligands: G9Y
 |
Crebbp Bromodomain In Complex With Cpd3 ((S)-1-(3-(6-(1-Methyl-1H-Pyrazol-4-Yl)-3,4-Dihydroquinolin-1(2H)-Yl)-1-(Tetrahydrofuran-3-Yl)-1,4,6,7-Tetrahydro-5H-Pyrazolo[4,3-C]Pyridin-5-Yl)Ethan-1-One)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.60 Å Release Date: 2018-03-07 Classification: TRANSCRIPTION REGULATOR/INHIBITOR Ligands: 9U7 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2018-03-07
Ligands: 9U7
 |
Crebbp Bromodomain In Complex With Cpd8 (1-(3-(7-(Difluoromethyl)-6-(1-Methyl-1H-Pyrazol-4-Yl)-3,4-Dihydroquinolin-1(2H)-Yl)-1-(Tetrahydrofuran-3-Yl)-1,4,6,7-Tetrahydro-5H-Pyrazolo[4,3-C]Pyridin-5-Yl)Ethan-1-One)
Organism: Mus musculus
Method: X-RAY DIFFRACTION Resolution:1.43 Å Release Date: 2018-03-07 Classification: TRANSFERASE/INHIBITOR Ligands: 9UA, DMS, GOL |
Organism: Mus musculus
Method: X-RAY DIFFRACTION
Release Date: 2018-03-07
Ligands: 9UA, DMS, GOL
 |
Crebbp Bromodomain In Complex With Cpd10 (1-(3-(7-(Difluoromethyl)-6-(1-Methyl-1H-Pyrazol-4-Yl)-3,4-Dihydroquinolin-1(2H)-Yl)-1-(Tetrahydro-2H-Pyran-4-Yl)-1,4,6,7-Tetrahydro-5H-Pyrazolo[4,3-C]Pyridin-5-Yl)Ethan-1-One)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.55 Å Release Date: 2018-03-07 Classification: TRANSCRIPTION REGULATOR/INHIBITOR Ligands: 9UD |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2018-03-07
Ligands: 9UD
 |
Crebbp Bromodomain In Complex With Cpd17 (N,2,7-Trimethyl-2,3-Dihydro-4H-Benzo[B][1,4]Oxazine-4-Carboxamide)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.70 Å Release Date: 2018-03-07 Classification: TRANSCRIPTION REGULATOR/INHIBITOR Ligands: SO4, 9UG |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2018-03-07
Ligands: SO4, 9UG