Search Count: 21
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X-Ray Co-Crystal Structure Of Ncgc00685960 / Ncats-Sm9335 In Nnmt
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.41 Å Release Date: 2025-03-05 Classification: TRANSFERASE Ligands: A1AF6 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-03-05
Ligands: A1AF6
 |
Myeloid Cell Leukemia-1 (Mcl-1) Complexed With Compound
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.90 Å Release Date: 2024-08-07 Classification: APOPTOSIS Ligands: A1ALT |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-08-07
Ligands: A1ALT
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Human Lactate Dehydrogenase A In Complex With Inhibitor Chk-336
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.34 Å Release Date: 2024-01-24 Classification: OXIDOREDUCTASE Ligands: NAI, YBO, EDO, PEG |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-01-24
Ligands: NAI, YBO, EDO, PEG
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Crystal Structure Of Human Wd Repeat-Containing Protein 5 In Complex With 4-(3,5-Dimethoxybenzyl)-9-(4-Fluoro-2-Methylphenyl)-7-((2-Imino-3-Methyl-2,3-Dihydro-1H-Imidazol-1-Yl)Methyl)-3,4-Dihydrobenzo[F][1,4]Oxazepin-5(2H)-One (Compound 8)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.01 Å Release Date: 2023-12-20 Classification: TRANSCRIPTION Ligands: VV3 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2023-12-20
Ligands: VV3
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Wd Repeat-Containing Protein 5 Complexed With 4-(7-((1H-Imidazol-1-Yl)Methyl)-5-(1-Methyl-3-(Trifluoromethyl)-1H-Pyrazol-4-Yl)-1-Oxo-3,4-Dihydroisoquinolin-2(1H)-Yl)-6-Ethyl-N-Methylquinoline-8-Carboxamide (Compound 10)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.55 Å Release Date: 2023-01-11 Classification: TRANSCRIPTION Ligands: BEN, UY9 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2023-01-11
Ligands: BEN, UY9
 |
Discovery Of Potent Orally Bioavailable Wd Repeat Domain 5 (Wdr5) Inhibitors Using A Pharmacophore-Based Optimization
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.81 Å Release Date: 2022-05-04 Classification: Transcription/Transcription Inhibitor Ligands: MBU |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2022-05-04
Ligands: MBU
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Wdr5 Bound To 2-(3,5-Dimethoxybenzyl)-7-((2-Methyl-1H-Imidazol-1-Yl)Methyl)-5-(1-Methyl-3-(Trifluoromethyl)-1H-Pyrazol-4-Yl)-3,4-Dihydroisoquinolin-1(2H)-One
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.90 Å Release Date: 2022-04-27 Classification: Transcription/Transcription Inhibitor Ligands: BEN, M4U |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2022-04-27
Ligands: BEN, M4U
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Crystal Structure Of Human Lactate Dehydrogenase A With Inhibitor Compound 15
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.50 Å Release Date: 2021-07-14 Classification: OXIDOREDUCTASE Ligands: NAI, SO4, EDO, GOL, PEG, YOJ |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2021-07-14
Ligands: NAI, SO4, EDO, GOL, PEG, YOJ
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Crystal Structure Of Ldha In Complex With Compound Ncgc00384414-01 At 2.05 A Resolution
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.05 Å Release Date: 2020-09-23 Classification: OXIDOREDUCTASE/OXIDOREDUCTASE inhibitor Ligands: PO4, P8M, NAI, GOL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-09-23
Ligands: PO4, P8M, NAI, GOL
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Crystal Structure Of Ldha In Complex With Compound Ncgc00420737-09 At 2.00 A Resolution
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.00 Å Release Date: 2020-09-23 Classification: OXIDOREDUCTASE/OXIDOREDUCTASE inhibitor Ligands: NAI, P8V, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-09-23
Ligands: NAI, P8V, EDO
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Discovery And Structure-Based Optimization Of Potent And Selective Wdr5 Inhibitors Containing A Dihydroisoquinolinone Bicyclic Core
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.85 Å Release Date: 2020-01-01 Classification: TRANSCRIPTION Ligands: Q41 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-01-01
Ligands: Q41
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Wd Repeat-Containing Protein 5 Complexed With N-[(3,5-Dimethoxyphenyl)Methyl]-4'-Fluoro-5-{[(2E)-2-Imino-3-Methyl-2,3-Dihydro-1H-Imidazol-1-Yl]Methyl}-2'-Methyl[1,1'-Biphenyl]-3-Carboxamide (Compound 13)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.02 Å Release Date: 2020-01-01 Classification: GENE REGULATION/INHIBITOR Ligands: Q6S |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-01-01
Ligands: Q6S
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Crystal Structure Of Lactate Dehydrogenase A In Complex With Inhibitor Compound 11
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.80 Å Release Date: 2018-01-17 Classification: OXIDOREDUCTASE Ligands: 9Y1, ACT, DMS, MLA, GOL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2018-01-17
Ligands: 9Y1, ACT, DMS, MLA, GOL
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Crystal Structure Of Lactate Dehydrogenase A In Complex With Inhibitor Compound 23 And Zinc
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.95 Å Release Date: 2018-01-17 Classification: OXIDOREDUCTASE Ligands: ZN, 9YD, CIT, DMS, MLA, GOL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2018-01-17
Ligands: ZN, 9YD, CIT, DMS, MLA, GOL
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Crystal Structure Of Lactate Dehydrogenase A In Complex With Inhibitor Compound 29
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.55 Å Release Date: 2018-01-17 Classification: OXIDOREDUCTASE Ligands: 9Y7, MLA, DMS, GOL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2018-01-17
Ligands: 9Y7, MLA, DMS, GOL
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Crystal Structure Of Lactate Dehydrogenase A In Complex With Inhibitor Compound 29 And Nadh
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.60 Å Release Date: 2018-01-17 Classification: OXIDOREDUCTASE Ligands: 9Y7, NAI, MLA, GOL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2018-01-17
Ligands: 9Y7, NAI, MLA, GOL
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Crystal Structure Of Lactate Dehydrogenase A In Complex With Inhibitor Compound 59 And Nadh
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.95 Å Release Date: 2018-01-17 Classification: OXIDOREDUCTASE Ligands: NAI, 9YA, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2018-01-17
Ligands: NAI, 9YA, EDO
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Benzofuropyrimidinone Inhibitors Of Pim-1
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.60 Å Release Date: 2013-01-16 Classification: TRANSFERASE Ligands: IMD, 79O |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-01-16
Ligands: IMD, 79O
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Benzofuropyrimidinone Inhibitors Of Pim-1
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.59 Å Release Date: 2013-01-16 Classification: TRANSFERASE Ligands: IMD, R9P |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-01-16
Ligands: IMD, R9P
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Benzofuropyrimidinone Inhibitors Of Pim-1
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.92 Å Release Date: 2013-01-16 Classification: TRANSFERASE Ligands: IMD, HY7 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-01-16
Ligands: IMD, HY7