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9Y0G image
Crystal Structure Of Nras-G12D In Complex With Gdp And Compound 1
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Resolution:1.80 Å Release Date: 2026-02-25
Classification: HYDROLASE
Ligands: GDP, A1CRR, MG, CIT

9Y1W image
Crystal Structure Of Nras-G12D In Complex With Gdp And Compound 27
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Resolution:1.95 Å Release Date: 2026-02-25
Classification: HYDROLASE
Ligands: GDP, MG, A1CRV, CIT

9Y1X image
Crystal Structure Of Nras-G12D In Complex With Gdp And Iacs-56676
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Resolution:1.72 Å Release Date: 2026-02-25
Classification: HYDROLASE
Ligands: GDP, A1CRW, MG, CIT

9Y1Y image
Crystal Structure Of Nras-G12D In Complex With Gdp And Compound 7
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Resolution:1.70 Å Release Date: 2026-02-25
Classification: HYDROLASE
Ligands: GDP, MG, A1CR1, CIT

9Y1Z image
Crystal Structure Of Nras-G12D In Complex With Gdp And Compound 5
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Resolution:1.92 Å Release Date: 2026-02-25
Classification: HYDROLASE
Ligands: GDP, MG, A1CR2, CIT

9Y3W image
Crystal Structure Of Nras-G12D In Complex With Gdp And Compound 13
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Resolution:1.56 Å Release Date: 2026-02-25
Classification: HYDROLASE
Ligands: GDP, MG, A1CSD, CIT

9CVD image
Set Domain Of Histone-Lysine N-Methyltransferase Nsd2 In Complex With Selective Inhibitor
Organism: Homo sapiens
Method: SOLUTION NMR
Release Date: 2025-04-30
Classification: TRANSFERASE/TRANSFERASE INHIBITOR
Ligands: ZN, A1A0M

8OUR image
Crystal Structure Of Dlk In Complex With Compound 16
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Resolution:1.95 Å Release Date: 2023-07-26
Classification: SIGNALING PROTEIN
Ligands: W38

8OUS image
Crystal Structure Of Dlk In Complex With Compound 19
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Resolution:2.20 Å Release Date: 2023-07-26
Classification: SIGNALING PROTEIN
Ligands: W3I

8OUT image
Crystal Structure Of Dlk In Complex With Compound 22
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Resolution:1.94 Å Release Date: 2023-07-26
Classification: SIGNALING PROTEIN
Ligands: W3C

7B1O image
Crystal Structure Of The Indoleamine 2,3-Dioxygenase 1 (Ido1) In Complex With Compound 22
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Resolution:2.58 Å Release Date: 2021-09-29
Classification: IMMUNOSUPPRESSANT
Ligands: SLW

7M63 image
Crystal Structure Of The Indoleamine 2,3-Dioxygenagse 1 (Ido1) Complexed With Iacs-70099
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Resolution:3.10 Å Release Date: 2021-09-01
Classification: HYDROLASE/HYDROLASE INHIBITOR
Ligands: YRP

7M7D image
Crystal Structure Of The Indoleamine 2,3-Dioxygenagse 1 (Ido1) Complexed With Iacs-8968
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Resolution:2.60 Å Release Date: 2021-09-01
Classification: HYDROLASE/HYDROLASE INHIBITOR
Ligands: YRM, HEM

4QT1 image
Jak3 Kinase Domain In Complex With 1-[(3S)-1-Isobutylsulfonyl-3-Piperidyl]-3-(5H-Pyrrolo[2,3-B]Pyrazin-2-Yl)Urea
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Resolution:2.40 Å Release Date: 2015-05-27
Classification: TRANSFERASE/TRANSFERASE INHIBITOR
Ligands: 3C9

4OT5 image
Crystal Structure Of Btk Kinase Domain Complexed With 4-Tert-Butyl-N-(3-{8-[4-(4-Methyl-Piperazine-1-Carbonyl)-Phenylamino]-Imidazo[1,2-A]Pyrazin-6-Yl}-Phenyl)-Benzamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Resolution:1.55 Å Release Date: 2014-05-14
Classification: TRANSFERASE/TRANSFERASE INHIBITOR
Ligands: 481, DMS

4OT6 image
Crystal Structure Of Btk Kinase Domain Complexed With 4-Methanesulfonyl-N-(3-{8-[4-(Morpholine-4-Carbonyl)-Phenylamino]-Imidazo[1,2-A]Pyrazin-6-Yl}-Phenyl)-Benzamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Resolution:2.05 Å Release Date: 2014-05-14
Classification: TRANSFERASE/TRANSFERASE INHIBITOR
Ligands: 2V1

4OTQ image
Crystal Structure Of Btk Kinase Domain Complexed With 1-[5-[3-(7-Tert-Butyl-4-Oxo-Quinazolin-3-Yl)-2-Methyl-Phenyl]-1-Methyl-2-Oxo-3-Pyridyl]-3-Methyl-Urea
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Resolution:1.55 Å Release Date: 2014-05-14
Classification: TRANSFERASE/TRANSFERASE INHIBITOR
Ligands: 2V2, DMS

4OTR image
Crystal Structure Of Btk Kinase Domain Complexed With 6-Cyclopropyl-2-[3-[5-[[5-(4-Ethylpiperazin-1-Yl)-2-Pyridyl]Amino]-1-Methyl-6-Oxo-3-Pyridyl]-2-(Hydroxymethyl)Phenyl]-8-Fluoro-Isoquinolin-1-One
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Resolution:1.95 Å Release Date: 2014-05-14
Classification: TRANSFERASE/TRANSFERASE INHIBITOR
Ligands: 2V3, DMS

3ZEP image
Crystal Structure Of Jak3 Kinase Domain In Complex With A Pyrrolopyrazine-2-Phenyl Ether Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Resolution:2.35 Å Release Date: 2013-12-11
Classification: TRANSFERASE
Ligands: 1NX, GOL

4I6Q image
Jak3 Kinase Domain In Complex With 2-Phenoxy-5H-Pyrrolo[2,3-B]Pyrazine-7-Carboxylic Acid ((S)-1-Cyclopropyl-Ethyl)-Amide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Resolution:1.85 Å Release Date: 2013-10-16
Classification: Transferase/Transferase Inhibitor
Ligands: PHU, 1DT
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