Search Count: 81
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Crystal Structure Of Cyp46A1 With [(1R,5S)-3-Oxa-8-Azabicyclo[3.2.1]Octan-8-Yl][(4R,8M)-8-(1,3-Oxazol-5-Yl)-6-(Trifluoromethyl)Imidazo[1,2-A]Pyridin-3-Yl]Methanone (Compound 3K)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.67 Å Release Date: 2025-07-02 Classification: HYDROLASE/INHIBITOR Ligands: HEM, A1BZE |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-07-02
Ligands: HEM, A1BZE
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Crystal Structure Of Cyp46A1 With (Morpholin-4-Yl)[(4R,8M)-8-(1,3-Oxazol-5-Yl)-6-(Trifluoromethyl)Imidazo[1,2-A]Pyridin-3-Yl]Methanone (Compound 2H)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.95 Å Release Date: 2025-07-02 Classification: HYDROLASE/INHIBITOR Ligands: HEM, A1BZD |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-07-02
Ligands: HEM, A1BZD
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Crystal Structure Of Cyp46A1 With Cyclopropyl[(4M)-4-(1,3-Oxazol-5-Yl)-6-(Trifluoromethyl)-1H-Indol-1-Yl]Methanone (Compound 2B)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.70 Å Release Date: 2025-07-02 Classification: HYDROLASE/INHIBITOR Ligands: HEM, A1BZC, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-07-02
Ligands: HEM, A1BZC, EDO
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Crystal Structure Of Cyp46A1 With 3-Chloro-N-[(3M)-3-(1,3-Oxazol-5-Yl)Phenyl]-N-(Propan-2-Yl)Benzene-1-Sulfonamide (Compound 2)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.29 Å Release Date: 2025-04-23 Classification: HYDROLASE/INHIBITOR Ligands: HEM, A1BZB, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-04-23
Ligands: HEM, A1BZB, EDO
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Crystal Structure Of Cyp46A1 With 3-Chloro-N-[(3M)-3-(1,3-Oxazol-5-Yl)-5-(Trifluoromethyl)Phenyl]Benzamide (Compound 3F)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.70 Å Release Date: 2025-04-23 Classification: HYDROLASE/INHIBITOR Ligands: HEM, A1BZA |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-04-23
Ligands: HEM, A1BZA
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Crystal Structure Of Cyp46A1 With N-[6-(1,3-Oxazol-5-Yl)-4-(Trifluoromethyl)Pyridin-2-Yl]Cyclopropanecarboxamide (Compound 4L)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.80 Å Release Date: 2025-04-23 Classification: HYDROLASE/INHIBITOR Ligands: HEM, A1BY9, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-04-23
Ligands: HEM, A1BY9, EDO
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Crystal Structure Of Dlk With Inhibitor Bound
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.38 Å Release Date: 2025-02-19 Classification: TRANSFERASE/INHIBITOR Ligands: A1AZP |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-02-19
Ligands: A1AZP
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Crystal Structure Of Dlk With Inhibitor Bound
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.50 Å Release Date: 2025-02-19 Classification: TRANSFERASE/INHIBITOR Ligands: A1AZ8, MG, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-02-19
Ligands: A1AZ8, MG, EDO
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Crystal Structure Of Wild Type Egfr In Complex With Tak-788
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.61 Å Release Date: 2022-12-07 Classification: HYDROLASE Ligands: R28 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2022-12-07
Ligands: R28
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Crystal Structure Of Egfr_D770_N771Insnpg/V948R In Complex With Tak-788
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.20 Å Release Date: 2022-12-07 Classification: HYDROLASE/HYDROLASE Inhibitor Ligands: R28, EDO, CIT |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2022-12-07
Ligands: R28, EDO, CIT
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Crystal Structure Of Human D-Amino Acid Oxidase In Complex With Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.10 Å Release Date: 2022-06-08 Classification: OXIDOREDUCTASE/INHIBITOR Ligands: FAD, M7I |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2022-06-08
Ligands: FAD, M7I
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Crystal Structure Of Human D-Amino Acid Oxidase In Complex With Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.66 Å Release Date: 2022-06-08 Classification: OXIDOREDUCTASE/INHIBITOR Ligands: FAD, BEZ, M89 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2022-06-08
Ligands: FAD, BEZ, M89
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Structure Of Hsting In Complex With Novel Carbocyclic Pyrimidine Cdn-2
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.35 Å Release Date: 2022-02-09 Classification: IMMUNE SYSTEM Ligands: X5D |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2022-02-09
Ligands: X5D
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Structure Of Hsting In Complex With Novel Carbocyclic Pyrimidine Cdn 1
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.48 Å Release Date: 2021-06-02 Classification: IMMUNE SYSTEM Ligands: X5J |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2021-06-02
Ligands: X5J
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Structure Of Hsting In Complex With Novel Carbocyclic Pyrimidine Cdn-3
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.80 Å Release Date: 2021-06-02 Classification: IMMUNE SYSTEM Ligands: X4M |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2021-06-02
Ligands: X4M
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Crystal Structure Of Tyk2 With Novel Pyrrolidinone Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.50 Å Release Date: 2020-02-12 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: N9G |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-02-12
Ligands: N9G
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Discovery Of A Novel, Highly Potent, And Selective Thieno[3,2-D]Pyrimidinone-Based Cdc7 Inhibitor With A Quinuclidine Moiety (Tak-931) As An Orally Active Investigational Anti-Tumor Agent
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.65 Å Release Date: 2020-01-15 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: O1S |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-01-15
Ligands: O1S
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Discovery Of A Novel, Highly Potent, And Selective Thieno[3,2-D]Pyrimidinone-Based Cdc7 Inhibitor With A Quinuclidine Moiety (Tak-931) As An Orally Active Investigational Anti-Tumor Agent
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:3.30 Å Release Date: 2020-01-15 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: O1V |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-01-15
Ligands: O1V
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Structure Of Rorgt In Complex With A Novel Inverse Agonist.
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.47 Å Release Date: 2019-07-17 Classification: nuclear protein/agonist Ligands: SO4, MPD, HQ7 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2019-07-17
Ligands: SO4, MPD, HQ7
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Structure Of Rorgt In Complex With A Novel Agonist.
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.10 Å Release Date: 2019-06-12 Classification: nuclear protein/agonist Ligands: EDO, HOJ |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2019-06-12
Ligands: EDO, HOJ