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Structure Of Kras-G12C Bound To 1-[(4Ar,10P,13R)-10-[5-Amino-4-Fluoro-3-Methyl-2-(Trifluoromethyl)Phenyl]-11-Chloro-9-Fluoro-1,2,4A,5-Tetrahydropyrazino[1',2':4,5][1,4]Oxazino[2,3-C]Quinolin-3(4H)-Yl]Prop-2-En-1-One (Compound 15)
Organism: Homo sapiens, Synthetic construct
Method: X-RAY DIFFRACTION Resolution:1.94 Å Release Date: 2026-03-11 Classification: ONCOPROTEIN Ligands: MG, GDP, A1CII, PEG, GOL, DMS, ACT |
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Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.84 Å Release Date: 2026-03-11 Classification: ONCOPROTEIN Ligands: A1CQ2, GDP, MG |
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Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.17 Å Release Date: 2026-03-11 Classification: ONCOPROTEIN Ligands: GDP, MG, DMS, EDO, A1AWR, PEG |
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Organism: Homo sapiens
Method: ELECTRON MICROSCOPY Resolution:2.60 Å Release Date: 2025-11-05 Classification: TRANSFERASE Ligands: A1BWF |
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Crystal Structure Of Selective Ire1A Inhibitor 29 At The Enzyme Active Site
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.43 Å Release Date: 2024-05-29 Classification: TRANSFERASE/INHIBITOR Ligands: EDO, XOE |
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Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.45 Å Release Date: 2021-04-21 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: N8S, EPE |
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Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.40 Å Release Date: 2021-04-21 Classification: TRANSFERASE/INHIBITOR Ligands: N97 |
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Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.54 Å Release Date: 2021-04-21 Classification: TRANSFERASE/TRANSFERASE INHIBITOR |
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Crystal Structure Of The Non-Ribose Partial Agonist Luf5833 Bound To The Adenosine A2A Receptor
Organism: Homo sapiens, Escherichia coli
Method: X-RAY DIFFRACTION Resolution:3.12 Å Release Date: 2021-04-07 Classification: MEMBRANE PROTEIN Ligands: RVZ, OLA, CLR, NA |
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Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.74 Å Release Date: 2020-12-09 Classification: TRANSFERASE Ligands: SJG |
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Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.61 Å Release Date: 2020-12-09 Classification: TRANSFERASE Ligands: SJM |
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Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.57 Å Release Date: 2020-12-09 Classification: TRANSFERASE |
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Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.30 Å Release Date: 2020-12-09 Classification: TRANSFERASE |
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Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.74 Å Release Date: 2020-12-09 Classification: TRANSFERASE Ligands: SJV |
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Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.08 Å Release Date: 2020-12-09 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: SJS |
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Structure Of The (Sr) Ca2+-Atpase Bound To The Inhibitor Compound Cad204520 And Tnp-Atp
Organism: Oryctolagus cuniculus
Method: X-RAY DIFFRACTION Resolution:3.40 Å Release Date: 2020-05-20 Classification: HYDROLASE Ligands: 128, OHW, K |
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Pcsk9-Fab 7G7 Complex Bound To Cis-1-Amino-4-Phenylcyclohexaneacyl-Wnlk(Hr)Igllr - Nh2
Organism: Homo sapiens, Mus musculus, Synthetic construct
Method: X-RAY DIFFRACTION Resolution:2.94 Å Release Date: 2020-02-05 Classification: HYDROLASE/HYDROLASE INHIBITOR/IMMUNE SYSTEM Ligands: CA |
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Organism: Homo sapiens, Mus musculus
Method: X-RAY DIFFRACTION Resolution:2.90 Å Release Date: 2020-02-05 Classification: HYDROLASE/HYDROLASE INHIBITOR/IMMUNE SYSTEM Ligands: CA |
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Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.20 Å Release Date: 2019-11-06 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: QFV, GOL |
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Structures Of The Pka Ri Alpha Holoenzyme With The Flhcc Driver J-Pkac Alpha Or Native Pkac Alpha
Organism: Homo sapiens, Bos taurus
Method: X-RAY DIFFRACTION Resolution:3.66 Å Release Date: 2019-04-03 Classification: SIGNALING PROTEIN Ligands: ATP, MG |