Search Count: 6
 |
Crystal Structure Of Human Wee1 Kinase Domain In Complex With Zn-C3
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.65 Å Release Date: 2021-09-01 Classification: TRANSFERASE Ligands: 05J |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2021-09-01
Ligands: 05J
 |
Discovery Of Mk-8353: An Orally Bioavailable Dual Mechanism Erk Inhibitor For Oncology
Organism: Rattus norvegicus
Method: X-RAY DIFFRACTION Resolution:1.45 Å Release Date: 2018-08-08 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: SO4, G67 |
Organism: Rattus norvegicus
Method: X-RAY DIFFRACTION
Release Date: 2018-08-08
Ligands: SO4, G67
 |
Discovery Of 3(S)-Thiomethyl Pyrrolidine Erk Inhibitors For Oncology
Organism: Rattus norvegicus
Method: X-RAY DIFFRACTION Resolution:1.85 Å Release Date: 2018-05-23 Classification: TRANSFERASE/TRANSFERASE inhibitor Ligands: SO4, F8V |
Organism: Rattus norvegicus
Method: X-RAY DIFFRACTION
Release Date: 2018-05-23
Ligands: SO4, F8V
 |
Dissecting Therapeutic Resistance To Erk Inhibition Rat Wild Type Sch772984 In Complex With (3R)-1-(2-Oxo-2-{4-[4-(Pyrimidin-2-Yl)Phenyl]Piperazin-1-Yl}Ethyl)-N-[3-(Pyridin-4-Yl)-2H-Indazol-5-Yl]Pyrrolidine-3-Carboxamide
Organism: Rattus norvegicus
Method: X-RAY DIFFRACTION Resolution:1.45 Å Release Date: 2016-02-24 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 38Z, SO4, PG4, DMS |
Organism: Rattus norvegicus
Method: X-RAY DIFFRACTION
Release Date: 2016-02-24
Ligands: 38Z, SO4, PG4, DMS
 |
Dissecting Therapeutic Resistance To Erk Inhibition Rat Mutant Sch772984 In Complex With (3R)-1-(2-Oxo-2-{4-[4-(Pyrimidin-2-Yl)Phenyl]Piperazin-1-Yl}Ethyl)-N-[3-(Pyridin-4-Yl)-2H-Indazol-5-Yl]Pyrrolidine-3-Carboxamide
Organism: Rattus norvegicus
Method: X-RAY DIFFRACTION Resolution:1.69 Å Release Date: 2016-02-24 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 38Z, SO4 |
Organism: Rattus norvegicus
Method: X-RAY DIFFRACTION
Release Date: 2016-02-24
Ligands: 38Z, SO4
 |
Discovery Of Novel, Dual Mechanism Erk Inhibitors By Affinity Selection Screening Of An Inactive Kinase State
Organism: Rattus norvegicus
Method: X-RAY DIFFRACTION Resolution:1.65 Å Release Date: 2014-11-12 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 3G7, SO4 |
Organism: Rattus norvegicus
Method: X-RAY DIFFRACTION
Release Date: 2014-11-12
Ligands: 3G7, SO4