Search Count: 53
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Structure Of Kras-G12C Bound To 1-[(4Ar,10P,13R)-10-[5-Amino-4-Fluoro-3-Methyl-2-(Trifluoromethyl)Phenyl]-11-Chloro-9-Fluoro-1,2,4A,5-Tetrahydropyrazino[1',2':4,5][1,4]Oxazino[2,3-C]Quinolin-3(4H)-Yl]Prop-2-En-1-One (Compound 15)
Organism: Homo sapiens, Synthetic construct
Method: X-RAY DIFFRACTION Resolution:1.94 Å Release Date: 2026-03-11 Classification: ONCOPROTEIN Ligands: MG, GDP, A1CII, PEG, GOL, DMS, ACT |
Organism: Homo sapiens, Synthetic construct
Method: X-RAY DIFFRACTION
Release Date: 2026-03-11
Ligands: MG, GDP, A1CII, PEG, GOL, DMS, ACT
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Human Ebp Complexed With Compound 1
Organism: Homo sapiens
Method: ELECTRON MICROSCOPY Release Date: 2024-06-19 Classification: ISOMERASE/INHIBITOR Ligands: A1AEU |
Organism: Homo sapiens
Method: ELECTRON MICROSCOPY
Release Date: 2024-06-19
Ligands: A1AEU
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Human Ebp Complexed With Compound 3A
Organism: Homo sapiens
Method: ELECTRON MICROSCOPY Release Date: 2024-06-19 Classification: ISOMERASE/INHIBITOR Ligands: A1AEV |
Organism: Homo sapiens
Method: ELECTRON MICROSCOPY
Release Date: 2024-06-19
Ligands: A1AEV
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Crystal Structure Of Pi3K-Alpha In Complex With Taselisib
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.99 Å Release Date: 2022-11-30 Classification: CELL CYCLE Ligands: 799 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2022-11-30
Ligands: 799
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Crystal Structure Of Pi3K-Alpha In Complex With Compound 19
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.46 Å Release Date: 2022-11-30 Classification: CELL CYCLE Ligands: X3W |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2022-11-30
Ligands: X3W
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Crystal Structure Of Pi3K-Alpha In Complex With Compound 30
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.68 Å Release Date: 2022-11-30 Classification: CELL CYCLE Ligands: X3R |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2022-11-30
Ligands: X3R
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Crystal Structure Of Pi3K-Alpha In Complex With Compound 32
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.48 Å Release Date: 2022-11-30 Classification: CELL CYCLE Ligands: X3N |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2022-11-30
Ligands: X3N
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Crystal Structure Of Hpk1 In Complex With Compound 2
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.33 Å Release Date: 2022-01-05 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 2YE |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2022-01-05
Ligands: 2YE
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Crystal Structure Of Hpk1 In Complex With Gne1858
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.50 Å Release Date: 2022-01-05 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: F97, EDO, MES |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2022-01-05
Ligands: F97, EDO, MES
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Crystal Structure Of Hpk1 In Complex With Compound 14
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.27 Å Release Date: 2022-01-05 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 2WI, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2022-01-05
Ligands: 2WI, SO4
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Crystal Structure Of Hpk1 In Complex With Compound 17
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.00 Å Release Date: 2022-01-05 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 2TR |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2022-01-05
Ligands: 2TR
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Structure Of The Vps34 Kinase Domain With Compound 14
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.88 Å Release Date: 2021-11-24 Classification: TRANSFERASE/TRANSFERASE inhibitor |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2021-11-24
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Structure Of The Vps34 Kinase Domain With Compound 14
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.67 Å Release Date: 2021-11-24 Classification: TRANSFERASE/TRANSFERASE inhibitor Ligands: GOL, 7IK |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2021-11-24
Ligands: GOL, 7IK
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Structure Of The Vps34 Kinase Domain With Compound 5
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.78 Å Release Date: 2021-11-24 Classification: TRANSFERASE/TRANSFERASE inhibitor Ligands: 7IQ, GOL, NA |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2021-11-24
Ligands: 7IQ, GOL, NA
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Cdk2 In Complex With Cpd14 (5-Fluoro-4-(4-Methyl-5,6,7,8-Tetrahydro-4H-Pyrazolo[1,5-A]Azepin-3-Yl)-N-(5-(4-Methylpiperazin-1-Yl)Pyridin-2-Yl)Pyrimidin-2-Amine)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.00 Å Release Date: 2020-07-29 Classification: TRANSFERASE/TRANSFERASE inhibitor Ligands: N14 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-07-29
Ligands: N14
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Cdk6 In Complex With Cpd13 (R)-5-Fluoro-4-(4-Methyl-5,6,7,8-Tetrahydro-4H-Pyrazolo[1,5-A]Azepin-3-Yl)-N-(5-(4-Methylpiperazin-1-Yl)Pyridin-2-Yl)Pyrimidin-2-Amine
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.71 Å Release Date: 2020-07-29 Classification: TRANSFERASE/TRANSFERASE inhibitor Ligands: N1A |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-07-29
Ligands: N1A
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Cdk6 In Complex With Cpd24 N-(5-(6-Ethyl-2,6-Diazaspiro[3.3]Heptan-2-Yl)Pyridin-2-Yl)-5-Fluoro-4-(4-Methyl-5,6,7,8-Tetrahydro-4H-Pyrazolo[1,5-A]Azepin-3-Yl)Pyrimidin-2-Amine
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.98 Å Release Date: 2020-07-29 Classification: TRANSFERASE/TRANSFERASE inhibitor Ligands: N1J |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-07-29
Ligands: N1J
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Lactate Dehydrogenase In Complex With Inhibitor 6-(3-Aminophenyl)-3-((2-Chlorophenyl)Thio)-4-Hydroxy-6-(Thiophen-3-Yl)-5,6-Dihydro-2H-Pyran-2-One
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.05 Å Release Date: 2018-10-24 Classification: OXIDOREDUCTASE/Inhibitor Ligands: NAD, EPE, SO4, D4S |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2018-10-24
Ligands: NAD, EPE, SO4, D4S
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Lactate Dehydrogenase In Complex With Inhibitor (S)-5-((2-Chlorophenyl)Thio)-6'-((4-Fluorophenyl)Amino)-4-Hydroxy-2-(Thiophen-3-Yl)-2,3-Dihydro-[2,2'-Bipyridin]-6(1H)-One
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.70 Å Release Date: 2018-10-24 Classification: OXIDOREDUCTASE/Inhibitor Ligands: EPE, NAD, LAC, SO4, D47 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2018-10-24
Ligands: EPE, NAD, LAC, SO4, D47
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Lactate Dehydrogenase In Complex With Inhibitor (R)-3-((2-Chlorophenyl)Thio)-6-(3-((4-Fluorophenyl)Amino)Phenyl)-4-Hydroxy-6-(Thiophen-3-Yl)-5,6-Dihydro-2H-Pyran-2-One
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.95 Å Release Date: 2018-10-24 Classification: OXIDOREDUCTASE Ligands: NAD, EPE, SO4, D3S, LAC |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2018-10-24
Ligands: NAD, EPE, SO4, D3S, LAC