Search Count: 27
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Cryo-Em Structure Of Human Lphn2 (Adgrl2)/G13 Complex In Lipid Nanodiscs
Organism: Homo sapiens
Method: ELECTRON MICROSCOPY Release Date: 2025-11-12 Classification: SIGNALING PROTEIN Ligands: CLR |
Organism: Homo sapiens
Method: ELECTRON MICROSCOPY
Release Date: 2025-11-12
Ligands: CLR
 |
Crystal Structure Of Fgfr2 Kinase Domain Gatekeeper Mutant V564F In Complex With Covalent Compound 19
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.22 Å Release Date: 2021-02-10 Classification: SIGNALING PROTEIN Ligands: WFD, FLC, NA |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2021-02-10
Ligands: WFD, FLC, NA
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Crystal Structure Of Fgfr2 Kinase Domain Gatekeeper Mutant V564F In Complex With Covalent Compound 3
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.47 Å Release Date: 2021-02-10 Classification: SIGNALING PROTEIN Ligands: WF7, FLC, GOL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2021-02-10
Ligands: WF7, FLC, GOL
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Cps1 Bound To Allosteric Inhibitor H3B-374
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.62 Å Release Date: 2021-01-13 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 374, ZN, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2021-01-13
Ligands: 374, ZN, EDO
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Sf3B Spliceosomal Complex Bound To E7107
Organism: Homo sapiens
Method: ELECTRON MICROSCOPY Resolution:3.95 Å Release Date: 2018-06-20 Classification: SPLICING Ligands: 9B0, ZN, K |
Organism: Homo sapiens
Method: ELECTRON MICROSCOPY
Release Date: 2018-06-20
Ligands: 9B0, ZN, K
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Estrogen Receptor Alpha Y537S Covalently Bound To Antagonist H3B-5942.
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.89 Å Release Date: 2018-03-21 Classification: nuclear protein/antagonist Ligands: F3D, EDO, DMS |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2018-03-21
Ligands: F3D, EDO, DMS
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Estrogen Receptor Alpha Y537S Bound To Antagonist H3B-9224.
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.68 Å Release Date: 2018-03-21 Classification: nuclear protein/antagonist Ligands: F3D, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2018-03-21
Ligands: F3D, EDO
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Crystal Structure Of Fgfr1-Y563C (Fgfr4 Surrogate) Covalently Bound To H3B-6527
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.20 Å Release Date: 2017-05-24 Classification: transferase/transferase inhibitor Ligands: 9ES, SO4, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-05-24
Ligands: 9ES, SO4, EDO
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The Crystal Structure Of Human Nicotinamide Phosphoribosyltransferase (Nampt) In Complex With N-(4-{(S)-[1-(2-Methylpropyl)Piperidin-4-Yl]Sulfinyl}Benzyl)Furo[2,3-C]Pyridine-2-Carboxamide Inhibitor (Compound 21)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.72 Å Release Date: 2015-02-11 Classification: Transferase/Transferase inhibitor Ligands: 3TQ, PO4, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-02-11
Ligands: 3TQ, PO4, EDO
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Discovery Of Potent And Efficacious Cyanoguanidine-Containing Nicotinamide Phosphoribosyltransferase (Nampt) Inhibitors
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.69 Å Release Date: 2013-12-25 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: LTS, PO4, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-12-25
Ligands: LTS, PO4, EDO
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Discovery Of Potent And Efficacious Cyanoguanidine-Containing Nicotinamide Phosphoribosyltransferase (Nampt) Inhibitors
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.64 Å Release Date: 2013-12-25 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: LWW, PO4, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-12-25
Ligands: LWW, PO4, EDO
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Fragment-Based Identification Of Amides Derived From Trans-2-(Pyridin-3-Yl)Cyclopropanecarboxylic Acid As Potent Inhibitors Of Human Nicotinamide Phosphoribosyltransferase (Nampt)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.81 Å Release Date: 2013-09-25 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 20J, PO4, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-09-25
Ligands: 20J, PO4, EDO
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Fragment-Based Identification Of Amides Derived From Trans-2-(Pyridin-3-Yl)Cyclopropanecarboxylic Acid As Potent Inhibitors Of Human Nicotinamide Phosphoribosyltransferase (Nampt)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.55 Å Release Date: 2013-09-25 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 20M, PO4, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-09-25
Ligands: 20M, PO4, EDO
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Fragment-Based Identification Of Amides Derived From Trans-2-(Pyridin-3-Yl)Cyclopropanecarboxylic Acid As Potent Inhibitors Of Human Nicotinamide Phosphoribosyltransferase (Nampt)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.84 Å Release Date: 2013-09-25 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 20N, PO4, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-09-25
Ligands: 20N, PO4, EDO
 |
Fragment-Based Identification Of Amides Derived From Trans-2-(Pyridin-3-Yl)Cyclopropanecarboxylic Acid As Potent Inhibitors Of Human Nicotinamide Phosphoribosyltransferase (Nampt)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.75 Å Release Date: 2013-09-25 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: PO4, 1EB, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-09-25
Ligands: PO4, 1EB, EDO
 |
Fragment-Based Identification Of Amides Derived From Trans-2-(Pyridin-3-Yl)Cyclopropanecarboxylic Acid As Potent Inhibitors Of Human Nicotinamide Phosphoribosyltransferase (Nampt)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.50 Å Release Date: 2013-09-25 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 20P, PO4, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-09-25
Ligands: 20P, PO4, EDO
 |
Fragment-Based Identification Of Amides Derived From Trans-2-(Pyridin-3-Yl)Cyclopropanecarboxylic Acid As Potent Inhibitors Of Human Nicotinamide Phosphoribosyltransferase (Nampt)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.70 Å Release Date: 2013-09-25 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 20O, PO4, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-09-25
Ligands: 20O, PO4, EDO
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Identification Of Amides Derived From 1H-Pyrazolo[3,4-B]Pyridine-5-Carboxylic Acid As Potent Inhibitors Of Human Nicotinamide Phosphoribosyltransferase (Nampt)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.75 Å Release Date: 2013-09-25 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 20R, PO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-09-25
Ligands: 20R, PO4
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Identification Of Amides Derived From 1H-Pyrazolo[3,4-B]Pyridine-5-Carboxylic Acid As Potent Inhibitors Of Human Nicotinamide Phosphoribosyltransferase (Nampt)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.41 Å Release Date: 2013-09-25 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 20T, POP, PO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-09-25
Ligands: 20T, POP, PO4
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Discovery Of Potent And Efficacious Urea-Containing Nicotinamide Phosphoribosyltransferase (Nampt) Inhibitors With Reduced Cyp2C9 Inhibition Properties
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.20 Å Release Date: 2013-05-29 Classification: Transferase/Transferase inhibitor Ligands: 1LJ, PO4, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-05-29
Ligands: 1LJ, PO4, EDO