ISDA: 9E51

Deposition Date 2024-10-26

Release Date 2025-11-12

Last Version Date 2026-03-04

Entry Detail

PDB ID:

9E51

Keywords:

SIGNALING PROTEIN

Title:

Cryo-EM structure of human LPHN2 (ADGRL2)/G13 complex in lipid nanodiscs

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)

Expression System(s):

Spodoptera frugiperda

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

2.90 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

Download Validation Report

Macromolecular Entities

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Adhesion G protein-coupled re
Gene (Uniprot):ADGRL2
Chain IDs:D (auth: A)
Chain Length:325
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:O95490 Pfam ID:PF00002

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Isoform 2 of Guanine nucleoti
Gene (Uniprot):GNA13
Chain IDs:A (auth: B)
Chain Length:230
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:Q14344 Pfam ID:PF00503

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Guanine nucleotide-binding pr
Gene (Uniprot):GNB1
Chain IDs:B (auth: C)
Chain Length:340
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:P62873 Pfam ID:PF00400, PF25391

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Guanine nucleotide-binding pr
Gene (Uniprot):GNG2
Chain IDs:C (auth: D)
Chain Length:71
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:P59768 Pfam ID:PF00631

Ligand Molecules