Search Count: 35
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First-In-Class Small Molecule Inhibitors Of Polycomb Repressive Complex 1 (Prc1) Ring Domain
Organism: Homo sapiens
Method: SOLUTION NMR Release Date: 2021-06-16 Classification: GENE REGULATION Ligands: ZN, U9E |
Organism: Homo sapiens
Method: SOLUTION NMR
Release Date: 2021-06-16
Ligands: ZN, U9E
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Ring1B-Bmi1 Fusion In Closed Conformation
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.70 Å Release Date: 2021-04-14 Classification: LIGASE Ligands: ZN, EPE, GOL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2021-04-14
Ligands: ZN, EPE, GOL
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Inhibitor Compound-Induced Confrontational Change In Ring1B-Bmi1 Domain Structure
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:3.09 Å Release Date: 2021-04-14 Classification: LIGASE Ligands: ZN |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2021-04-14
Ligands: ZN
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Ash1L Set Domain In Complex With As-85
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.69 Å Release Date: 2021-04-07 Classification: PROTEIN BINDING, TRANSFERASE/INHIBITOR Ligands: EPE, SAM, ZN, UG7 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2021-04-07
Ligands: EPE, SAM, ZN, UG7
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Ash1L Set Domain Q2265A Mutant In Complex With As-5
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.69 Å Release Date: 2021-04-07 Classification: PROTEIN BINDING, TRANSFERASE/INHIBITOR Ligands: UK7, ZN, SAM |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2021-04-07
Ligands: UK7, ZN, SAM
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Nsd1 Set Domain In Complex With Sam
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.40 Å Release Date: 2020-09-02 Classification: TRANSFERASE Ligands: SAM, ZN |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-09-02
Ligands: SAM, ZN
 |
Nsd1 Set Domain In Complex With Bt3 And Sam
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.80 Å Release Date: 2020-09-02 Classification: TRANSFERASE Ligands: SAM, DQL, DW9, ZN, CA, GOL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-09-02
Ligands: SAM, DQL, DW9, ZN, CA, GOL
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Menin In Complex With Peptide Inhibitor 25
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.50 Å Release Date: 2020-09-02 Classification: PROTEIN BINDING/INHIBITOR Ligands: DMS, SO4, PG4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-09-02
Ligands: DMS, SO4, PG4
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Menin In Complex With Mi-3454
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.24 Å Release Date: 2020-01-08 Classification: PROTEIN BINDING Ligands: LMY, DMS, SO4, PG4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-01-08
Ligands: LMY, DMS, SO4, PG4
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Menin In Complex With Mi-1481
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.82 Å Release Date: 2018-11-28 Classification: Protein Binding, Transcription Ligands: EEV, DMS, PG4, SO4, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2018-11-28
Ligands: EEV, DMS, PG4, SO4, EDO
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Menin In Complex With Mi-1482
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.90 Å Release Date: 2018-11-28 Classification: PROTEIN BINDING Ligands: FNV, DMS, PG4, SO4, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2018-11-28
Ligands: FNV, DMS, PG4, SO4, EDO
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Menin In Complex With Mi-2-3
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.62 Å Release Date: 2016-07-06 Classification: PROTEIN BINDING/INHIBITOR Ligands: 59V, DMS, PGE, PEG, EPE |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-07-06
Ligands: 59V, DMS, PGE, PEG, EPE
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Menin In Complex With Mi-352
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.50 Å Release Date: 2016-03-30 Classification: PROTEIN BINDING/INHIBITOR Ligands: PG4, SO4, DMS, 58P, 6E6 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-03-30
Ligands: PG4, SO4, DMS, 58P, 6E6
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Menin In Complex With Mi-336
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.86 Å Release Date: 2016-03-30 Classification: PROTEIN BINDING/INHIBITOR Ligands: 58O, DMS, SO4, PG4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-03-30
Ligands: 58O, DMS, SO4, PG4
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Menin In Complex With Mi-389
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.54 Å Release Date: 2016-03-30 Classification: PROTEIN BINDING/INHIBITOR Ligands: 58R, DMS, PG4, SO4, PEG |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-03-30
Ligands: 58R, DMS, PG4, SO4, PEG
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Menin In Complex With Mi-574
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.71 Å Release Date: 2016-03-30 Classification: PROTEIN BINDING/INHIBITOR Ligands: DMS, PG4, SO4, PEG, 58Q |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-03-30
Ligands: DMS, PG4, SO4, PEG, 58Q
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Menin In Complex With Mi-326
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.62 Å Release Date: 2015-09-09 Classification: PROTEIN BINDING/INHIBITOR Ligands: 59K, DMS, PG4, PGE, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-09-09
Ligands: 59K, DMS, PG4, PGE, SO4
 |
Menin In Complex With Mi-333
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.83 Å Release Date: 2015-09-09 Classification: PROTEIN BINDING/INHIBITOR Ligands: 59M, DMS, PGE, EDO, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-09-09
Ligands: 59M, DMS, PGE, EDO, SO4
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Menin In Complex With Mi-319
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.54 Å Release Date: 2015-09-09 Classification: PROTEIN BINDING/INHIBITOR Ligands: 59Q, DMS, PG4, PEG, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-09-09
Ligands: 59Q, DMS, PG4, PEG, SO4
 |
Menin In Complex With Mi-836
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.14 Å Release Date: 2015-09-09 Classification: PROTEIN BINDING/INHIBITOR Ligands: 59X, SO4, DMS, PG4, PEG |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-09-09
Ligands: 59X, SO4, DMS, PG4, PEG