Search Count: 20
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Jak2 Kinase (Jh1 Domain) In Complex With Tg101209
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.40 Å Release Date: 2013-08-07 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 1M3 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-08-07
Ligands: 1M3
 |
Jak2 Kinase (Jh1 Domain) In Complex With Compound 9
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.85 Å Release Date: 2013-08-07 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 1K3, GOL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-08-07
Ligands: 1K3, GOL
 |
The Jak1 Kinase Domain In Complex With Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.10 Å Release Date: 2013-05-22 Classification: TRANSFERASE Ligands: C5I, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-05-22
Ligands: C5I, EDO
 |
Jak2 Kinase (Jh1 Domain) In Complex With The Inhibitor Trans-4-[(8As)-2-[(1R)-1-Hydroxyethyl]Imidazo[4,5-D]Pyrrolo[2,3-B]Pyridin-1(8Ah)-Yl]Cyclohexanecarbonitrile
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.50 Å Release Date: 2013-05-22 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 1J5 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-05-22
Ligands: 1J5
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Jak1 Kinase (Jh1 Domain) In Complex With The Inhibitor Trans-4-{2-[(1R)-1-Hydroxyethyl]Imidazo[4,5-D]Pyrrolo[2,3-B]Pyridin-1(6H)-Yl}Cyclohexanecarbonitrile
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.90 Å Release Date: 2013-05-22 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 1J5 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-05-22
Ligands: 1J5
 |
Jak1 Kinase (Jh1 Domain) In Complex With The Inhibitor (Trans-4-{2-[(1R)-1-Hydroxyethyl]Imidazo[4,5-D]Pyrrolo[2,3-B]Pyridin-1(6H)-Yl}Cyclohexyl)Acetonitrile
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.35 Å Release Date: 2013-05-22 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 1J6 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-05-22
Ligands: 1J6
 |
Jak1 Kinase (Jh1 Domain) In Complex With Compound 34
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.93 Å Release Date: 2013-05-22 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 15T |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-05-22
Ligands: 15T
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B-Raf Kinase Domain In Complex With An Aminothienopyrimidine-Based Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:3.30 Å Release Date: 2013-04-24 Classification: Transferase/Transferase Inhibitor Ligands: RI8 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-04-24
Ligands: RI8
 |
B-Raf Kinase Domain In Complex With An Aminopyridimine-Based Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:3.50 Å Release Date: 2013-04-24 Classification: Transferase/Transferase Inhibitor Ligands: RI9 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-04-24
Ligands: RI9
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Jak1 Kinase (Jh1 Domain) In Complex With Compound 72
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.20 Å Release Date: 2012-11-07 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 0UJ |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2012-11-07
Ligands: 0UJ
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The Jak1 Kinase Domain In Complex With Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.17 Å Release Date: 2012-07-04 Classification: Transferase/Transferase Inhibitor Ligands: JAK, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2012-07-04
Ligands: JAK, EDO
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Jak1 Kinase (Jh1 Domain) In Complex With Compound 20
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.22 Å Release Date: 2012-07-04 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 0Q2 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2012-07-04
Ligands: 0Q2
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Discovery And Optimization Of C-2 Methyl Imidazo-Pyrrolopyridines As Potent And Orally Bioavailable Jak1 Inhibitors With Selectivity Over Jak2
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.82 Å Release Date: 2012-07-04 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 1RS |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2012-07-04
Ligands: 1RS
 |
Discovery And Optimization Of C-2 Methyl Imidazo-Pyrrolopyridines As Potent And Orally Bioavailable Jak1 Inhibitors With Selectivity Over Jak2
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.40 Å Release Date: 2012-07-04 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: JAK |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2012-07-04
Ligands: JAK
 |
Non-Phosphorylated Tyk2 Jh1 Domain With Quinoline-Thiadiazole-Thiophene Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.50 Å Release Date: 2010-10-20 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: TZ1, DTT |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2010-10-20
Ligands: TZ1, DTT
 |
Non-Phosphorylated Tyk2 Kinase With Cmp6
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.00 Å Release Date: 2010-10-20 Classification: TRANSFERASE Ligands: IZA |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2010-10-20
Ligands: IZA
 |
Low Molecular Weigth Human Urokinase Type Plasminogen Activator 2-[6-(3'-Aminomethyl-Biphenyl-3-Yloxy)-4-(3-Dimethylamino-Pyrrolidin-1-Yl)-3,5-Difluoro-Pyridin-2-Yloxy]-4-Dimethylamino-Benzoic Acid Complex
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.83 Å Release Date: 2009-10-13 Classification: HYDROLASE Ligands: 438, PO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2009-10-13
Ligands: 438, PO4
 |
Aurora A In Complex With A Bisanilinopyrimidine
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.50 Å Release Date: 2009-07-07 Classification: TRANSFERASE Ligands: 48B, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2009-07-07
Ligands: 48B, SO4
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Aurora A In Complex With A Bisanilinopyrimidine
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.92 Å Release Date: 2009-07-07 Classification: TRANSFERASE Ligands: 45B |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2009-07-07
Ligands: 45B
 |
Aurora A Inhibitor Complex
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.20 Å Release Date: 2009-07-07 Classification: TRANSFERASE Ligands: 97B |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2009-07-07
Ligands: 97B