Search Count: 51
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Highly Optimized Cns Penetrant Inhibitors Of Egfr Exon20 Insertion Mutations
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.42 Å Release Date: 2025-02-12 Classification: SIGNALING PROTEIN Ligands: A1IZ7 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-02-12
Ligands: A1IZ7
 |
Highly Optimized Cns Penetrant Inhibitors Of Egfr Exon20 Insertion Mutations
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.91 Å Release Date: 2025-02-12 Classification: SIGNALING PROTEIN Ligands: A1IZ8, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-02-12
Ligands: A1IZ8, SO4
 |
Highly Optimized Cns Penetrant Inhibitors Of Egfr Exon20 Insertion Mutations
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.90 Å Release Date: 2025-02-12 Classification: SIGNALING PROTEIN Ligands: A1IZ9 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-02-12
Ligands: A1IZ9
 |
Highly Optimized Cns Penetrant Inhibitors Of Egfr Exon20 Insertion Mutations
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.22 Å Release Date: 2025-02-12 Classification: SIGNALING PROTEIN Ligands: Q6K, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-02-12
Ligands: Q6K, SO4
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Highly Optimized Cns Penetrant Inhibitors Of Egfr Exon20 Insertion Mutations. Compound 51 Bound To Egfrinsnpg [V948R]
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.45 Å Release Date: 2025-02-05 Classification: SIGNALING PROTEIN Ligands: A1IUK |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-02-05
Ligands: A1IUK
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Crystal Structure Of Parp1 Catalytic Domain Bound To Azd5305 (Saruparib)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.59 Å Release Date: 2024-12-04 Classification: TRANSFERASE Ligands: A1H63, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-12-04
Ligands: A1H63, SO4
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Crystal Structure Of Parp1 Catalytic Domain Bound To Azd9574
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.82 Å Release Date: 2024-12-04 Classification: TRANSFERASE Ligands: A1H64, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-12-04
Ligands: A1H64, SO4
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Optimisation Of Potent, Efficacious, Selective And Blood-Brain Barrier Penetrating Inhibitors Targeting Egfr Exon20 Insertion Mutations
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.44 Å Release Date: 2024-11-06 Classification: SIGNALING PROTEIN Ligands: A1H7N, IOD |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-11-06
Ligands: A1H7N, IOD
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Optimisation Of Potent, Efficacious, Selective And Blood-Brain Barrier Penetrating Inhibitors Targeting Egfr Exon20 Insertion Mutations
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:3.02 Å Release Date: 2024-10-16 Classification: SIGNALING PROTEIN Ligands: A1H7O |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-10-16
Ligands: A1H7O
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Crystal Structure Of Mus81-Eme1, Apo Form.
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.15 Å Release Date: 2024-07-03 Classification: HYDROLASE |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-07-03
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Crystal Structure Of Mus81-Eme1 Bound By Compound 15.
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.73 Å Release Date: 2024-07-03 Classification: HYDROLASE Ligands: MG, A1IA7 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-07-03
Ligands: MG, A1IA7
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Crystal Structure Of Mus81-Eme1 Bound By Compound 16.
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.02 Å Release Date: 2024-07-03 Classification: HYDROLASE Ligands: MG, EOH, A1IA8 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-07-03
Ligands: MG, EOH, A1IA8
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Crystal Structure Of Mus81-Eme1 Bound By Compound 10.
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.80 Å Release Date: 2024-06-19 Classification: HYDROLASE Ligands: A1IA5, MG |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-06-19
Ligands: A1IA5, MG
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Crystal Structure Of Mus81-Eme1 Bound By Compound 12.
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.91 Å Release Date: 2024-06-19 Classification: HYDROLASE Ligands: A1IA6, MG |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-06-19
Ligands: A1IA6, MG
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Crystal Structure Of Mus81-Eme1 Bound By Compound 21.
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.47 Å Release Date: 2024-06-19 Classification: HYDROLASE Ligands: MG, A1IA4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-06-19
Ligands: MG, A1IA4
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Discovery And Optimisation Of Potent, Efficacious And Selective Inhibitors Targeting Egfr Exon20 Insertion Mutations. Compound 16 Bound To Egfr
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.51 Å Release Date: 2024-06-05 Classification: SIGNALING PROTEIN Ligands: 2I0 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-06-05
Ligands: 2I0
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Discovery And Optimisation Of Potent, Efficacious And Selective Inhibitors Targeting Egfr Exon20 Insertion Mutations. Compound 12 Bound To Egfrinsnpg
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.52 Å Release Date: 2024-06-05 Classification: SIGNALING PROTEIN Ligands: 2I6 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-06-05
Ligands: 2I6
 |
Discovery And Optimisation Of Potent, Efficacious And Selective Inhibitors Targeting Egfr Exon20 Insertion Mutations. Compound 22 Bound To Egfrinsnpg [V948R]
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.11 Å Release Date: 2024-06-05 Classification: SIGNALING PROTEIN Ligands: 2EI, IOD |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-06-05
Ligands: 2EI, IOD
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Discovery And Optimisation Of Potent, Efficacious And Selective Inhibitors Targeting Egfr Exon20 Insertion Mutations. Compound 33 Bound To Egfrinsnpg [V948R]
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.28 Å Release Date: 2024-06-05 Classification: SIGNALING PROTEIN Ligands: 26X |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-06-05
Ligands: 26X
 |
Discovery And Optimisation Of Potent, Efficacious And Selective Inhibitors Targeting Egfr Exon20 Insertion Mutations. Compound 18 Bound To Egfr[V948R]
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.13 Å Release Date: 2024-06-05 Classification: SIGNALING PROTEIN Ligands: 2II |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-06-05
Ligands: 2II