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Crystal Structure Of Gdp-Bound Kras G12D/I55E: Suppressing G12D Oncogenicity Via Second-Site I55E Mutation
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.23 Å Release Date: 2026-03-25 Classification: ONCOPROTEIN Ligands: GDP, MG, CL |
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Structure Of Kras-G12C Bound To 1-[(4Ar,10P,13R)-10-[5-Amino-4-Fluoro-3-Methyl-2-(Trifluoromethyl)Phenyl]-11-Chloro-9-Fluoro-1,2,4A,5-Tetrahydropyrazino[1',2':4,5][1,4]Oxazino[2,3-C]Quinolin-3(4H)-Yl]Prop-2-En-1-One (Compound 15)
Organism: Homo sapiens, Synthetic construct
Method: X-RAY DIFFRACTION Resolution:1.94 Å Release Date: 2026-03-11 Classification: ONCOPROTEIN Ligands: MG, GDP, A1CII, PEG, GOL, DMS, ACT |
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Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.84 Å Release Date: 2026-03-11 Classification: ONCOPROTEIN Ligands: A1CQ2, GDP, MG |
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Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.17 Å Release Date: 2026-03-11 Classification: ONCOPROTEIN Ligands: GDP, MG, DMS, EDO, A1AWR, PEG |
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The Ubiquitin-Associated Domain Of Human Thirty-Eight Negative Kinase-1 Rigidly Fused To A Double Trigger Variant Of The 1Tel Crystallization Chaperone, Alternate Crystal Form
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.96 Å Release Date: 2026-03-04 Classification: ONCOPROTEIN Ligands: TLA, NA, SO4, TAR |
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Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.00 Å Release Date: 2026-02-18 Classification: ONCOPROTEIN |
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Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.65 Å Release Date: 2026-02-18 Classification: ONCOPROTEIN Ligands: A1I1A |
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Organism: Homo sapiens, Synthetic construct
Method: X-RAY DIFFRACTION Resolution:1.90 Å Release Date: 2026-02-18 Classification: ONCOPROTEIN Ligands: HHT, SO4 |
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Organism: Homo sapiens, Synthetic construct
Method: X-RAY DIFFRACTION Resolution:2.00 Å Release Date: 2026-02-18 Classification: ONCOPROTEIN Ligands: IJX, SO4 |
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Organism: Homo sapiens, Synthetic construct
Method: X-RAY DIFFRACTION Resolution:1.24 Å Release Date: 2026-02-18 Classification: ONCOPROTEIN Ligands: GDP, MG, GOL |
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Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.40 Å Release Date: 2026-01-21 Classification: ONCOPROTEIN Ligands: GDP, MG, 6IC, MPD, CL |
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Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.90 Å Release Date: 2026-01-21 Classification: ONCOPROTEIN Ligands: GNP, MG, 6IC, GOL, SO4, CL, NA |
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Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.50 Å Release Date: 2026-01-21 Classification: ONCOPROTEIN Ligands: GDP, MG, 6IC, CL |
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Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.90 Å Release Date: 2026-01-21 Classification: ONCOPROTEIN Ligands: GNP, MG, 6IC, SO4, GOL, CL |
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Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:3.46 Å Release Date: 2026-01-14 Classification: ONCOPROTEIN/INHIBITOR Ligands: ANP, MG, SO4, A1BIS |
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Identification And Non-Clinical Characterization Of Sar444200, A Novel Anti-Gpc3 T-Cell Engager For The Treatment Of Gpc3+ Solid Tumors
Organism: Homo sapiens, Lama glama
Method: ELECTRON MICROSCOPY Release Date: 2026-01-14 Classification: IMMUNE SYSTEM Ligands: NAG |
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A Darpin Fused To The 1Tel Crystallization Chaperone Via A Direct Helical Fusion
Organism: Homo sapiens, Synthetic construct
Method: X-RAY DIFFRACTION Resolution:1.24 Å Release Date: 2025-12-17 Classification: TRANSCRIPTION Ligands: AKG, NH4, GOL, EOH, K, CL, PO4 |
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Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.11 Å Release Date: 2025-12-10 Classification: ONCOPROTEIN Ligands: GDP, MG, EDO, A1BV7 |
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Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.70 Å Release Date: 2025-12-03 Classification: ONCOPROTEIN/INHIBITOR Ligands: GDP, MG, A1CG4 |
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Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.35 Å Release Date: 2025-12-03 Classification: ONCOPROTEIN/INHIBITOR Ligands: GNP, MG, A1CG4 |