ISDA: 9S84

Deposition Date 2025-08-05

Release Date 2026-06-10

Last Version Date 2026-06-10

Entry Detail

PDB ID:

9S84

Keywords:

ONCOPROTEIN

Title:

Crystal structure of KRAS G12D D38C (GDP-bound)

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)

Expression System(s):

Escherichia coli

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

1.64 Å

R-Value Free:

0.18

R-Value Work:

0.14

R-Value Observed:

0.14

Space Group:

P 41 21 2

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Macromolecular Entities

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:V-Ki-ras2 Kirsten rat sarcoma
Gene (Uniprot):KRAS
Chain IDs:A
Chain Length:170
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:A0ABF7PHA5

Ligand Molecules

EDO

GDP

NO3

Primary Citation

KRAS G12D D38C Structure

Zak, K.M, Kessler, D.Show

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Primary Citation of related structures

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