Search Count: 114
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Human Tead1 In Complex With 2-(4-Chloro-3-{3-Methyl-5-[4-(Trifluoromethyl)Phenoxy]Phenyl}-1H-Pyrrolo[3,2-C]Pyridin-1-Yl)Ethan-1-Ol
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.85 Å Release Date: 2026-02-04 Classification: TRANSCRIPTION Ligands: MYR, GOL, CL, A1JLZ |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2026-02-04
Ligands: MYR, GOL, CL, A1JLZ
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Focal Adhesion Kinase Catalytic Domain In Complex With 6-(1H-Pyrazol-4-Yl)-Nicotinic Acid
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.53 Å Release Date: 2025-12-31 Classification: TRANSFERASE Ligands: SO4, A1JNJ |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-12-31
Ligands: SO4, A1JNJ
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Crystal Structure Of Human Exonuclease 1 (Exo1) With Dna And Compound 20
Organism: Homo sapiens, Synthetic construct
Method: X-RAY DIFFRACTION Resolution:1.90 Å Release Date: 2025-12-17 Classification: HYDROLASE Ligands: MG, NA, A1JNC, FMT |
Organism: Homo sapiens, Synthetic construct
Method: X-RAY DIFFRACTION
Release Date: 2025-12-17
Ligands: MG, NA, A1JNC, FMT
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Crystal Structure Of Human Exonuclease 1 (Exo1) With Dna And Compound Art5537
Organism: Homo sapiens, Synthetic construct
Method: X-RAY DIFFRACTION Resolution:2.20 Å Release Date: 2025-12-17 Classification: HYDROLASE Ligands: MG, A1JO0, NA |
Organism: Homo sapiens, Synthetic construct
Method: X-RAY DIFFRACTION
Release Date: 2025-12-17
Ligands: MG, A1JO0, NA
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Tead1 In Complex With A Reversible Inhibitor N-[(1S)-2-Hydroxy-1-(1-Methyl-1H-Pyrazol-3-Yl)Ethyl]-2-Methyl-8-[4-(Trifluoromethyl)Phenyl]-2H,8H-Pyrazolo[3,4-B]Indole-5-Carboxamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.93 Å Release Date: 2025-01-22 Classification: TRANSCRIPTION Ligands: GOL, A1IJL, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-01-22
Ligands: GOL, A1IJL, SO4
 |
Human Nkp30 In Complex With A Vhh Variant
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.84 Å Release Date: 2024-10-30 Classification: IMMUNE SYSTEM Ligands: NAG |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-10-30
Ligands: NAG
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Vhh Variant Adression Natural Cytotoxicity Triggering Receptor 3
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.07 Å Release Date: 2024-10-30 Classification: IMMUNE SYSTEM Ligands: PO4, 12H |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-10-30
Ligands: PO4, 12H
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Tead1/Yap In Complex With A Reversible Inhibitor N-[(4-Phenoxyphenyl)Methyl]Imidazo[1,2-A]Pyridine-3-Carboxamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.21 Å Release Date: 2024-10-16 Classification: TRANSCRIPTION Ligands: CL, A1IHH |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-10-16
Ligands: CL, A1IHH
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Crystal Structure Of Human Hpk1 (Map4K1) Complex With 7-(1-Methyl-1H-Pyrazol-4-Yl)-N-[4-(1-Methylpiperidin-4-Yl)Phenyl]Quinazolin-2-Amine
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.94 Å Release Date: 2023-08-16 Classification: TRANSFERASE Ligands: UES |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2023-08-16
Ligands: UES
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Crystal Structure Of Human Hpk1 (Map4K1) Complex With 2-[8-Amino-7-Fluoro-6-(8-Methyl-2,3-Dihydro-1H-Pyrido[2,3-B][1,4]Oxazin-7-Yl)-Isoquinolin-3-Ylamino]-6-Isopropyl-5,6-Dihydro-4H-1,6,8A-Triaza-Azulen-7-One
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.82 Å Release Date: 2023-08-16 Classification: TRANSFERASE Ligands: USF |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2023-08-16
Ligands: USF
 |
Structure Of Hif2A-Arnt Heterodimer In Complex With (S)-1-(3,5-Difluoro-Phenyl)-5,5-Difluoro-3-Methanesulfonyl-5,6-Dihydro-4H-Cyclopenta[C]Thiophen-4-Ol
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.71 Å Release Date: 2023-07-19 Classification: TRANSCRIPTION Ligands: UXU, DMS |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2023-07-19
Ligands: UXU, DMS
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Structure Of Hif2A-Arnt Heterodimer In Complex With (4S)-1-(3,5-Difluorophenyl)-5,5-Difluoro-3-Methanesulfonyl-4,5,6,7-Tetrahydro-2-Benzothiophen-4-Ol
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.29 Å Release Date: 2023-07-19 Classification: TRANSCRIPTION Ligands: UY3 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2023-07-19
Ligands: UY3
 |
Structure Of Hif2A-Arnt Heterodimer In Complex With (S)-1-Cyclohexyloxy-5,5-Difluoro-3-Methanesulfonyl-5,6-Dihydro-4H-Cyclopenta[C]Thiophen-4-Ol
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.30 Å Release Date: 2023-07-19 Classification: TRANSCRIPTION Ligands: UYF |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2023-07-19
Ligands: UYF
 |
Human Wee1 Kinase In Complex With Inhibitor 1-[6-(1-Hydroxy-1-Methyl-Ethyl)-Pyridin-2-Yl]-2-(2-Methoxy-Phenyl)-6-[4-(4-Methyl-Piperazin-1-Yl)-Phenylamino]-1,2-Dihydro-Pyrazolo[3,4-D]Pyrimidin-3-One
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.53 Å Release Date: 2023-05-31 Classification: TRANSFERASE Ligands: QT9 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2023-05-31
Ligands: QT9
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Structure Of Human Plk1 In Complex With 2-Allyl-1-[6-(1-Hydroxy-1-Methyl-Ethyl)-Pyridin-2-Yl]-6-[4-(4-Methyl-Piperazin-1-Yl)-Phenylamino]-1,2-Dihydro-Pyrazolo[3,4-D]Pyrimidin-3-One
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.19 Å Release Date: 2023-04-26 Classification: TRANSFERASE Ligands: ACT, 8X7, ZN |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2023-04-26
Ligands: ACT, 8X7, ZN
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R399E, A Mutated Form Of Gdf5, For Disease Modification Of Osteoarthritis
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.30 Å Release Date: 2022-09-28 Classification: SIGNALING PROTEIN |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2022-09-28
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Optimization Of Tead P-Site Binding Fragment Hit Into In Vivo Active Lead Msc-4106
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.19 Å Release Date: 2022-07-13 Classification: TRANSCRIPTION Ligands: JJU, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2022-07-13
Ligands: JJU, SO4
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Human Tead3 In Complex With 1-Cyclopentyl-1H-Pyrazolo[3,4-B]Pyridine-5-Carboxylic Acid
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.10 Å Release Date: 2022-07-13 Classification: TRANSCRIPTION Ligands: JIK |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2022-07-13
Ligands: JIK
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Human Immunoproteasome 20S Particle In Complex With [2-(3-Ethylphenyl)-1-[(2S)-3-Phenyl-2-[(Pyrazin-2-Yl)Formamido]Propanamido]Ethyl]Boronic Acid
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.43 Å Release Date: 2021-12-01 Classification: IMMUNE SYSTEM Ligands: SO4, NA, SKN |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2021-12-01
Ligands: SO4, NA, SKN
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Human Tnks1 In Complex With 3-[4-(1-Hydroxy-1-Methyl-Ethyl)-Phenyl]-6-Methyl-2H-Pyrrolo[1,2-A]Pyrazin-1-One
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.43 Å Release Date: 2021-07-28 Classification: TRANSFERASE Ligands: ACT, V8B, ZN |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2021-07-28
Ligands: ACT, V8B, ZN