Search Count: 56
 |
Crystal Structure Of 11Beta-Hsd1 Double Mutant (L262R, F278E) Complexed With 2-(3-(1-(4-Chlorophenyl)Cyclopropyl) -[1,2,4]Triazolo[4,3-A]Pyridin-8-Yl)Propan-2-Ol
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.45 Å Release Date: 2018-12-19 Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR Ligands: NAP, HJG |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2018-12-19
Ligands: NAP, HJG
 |
Crystal Structure Of Murine 11B- Hydroxysteroiddehydrogenase Complexed With 2-(3-(1-(4- Chlorophenyl)Cyclopropyl)-[1,2,4]Triazolo[4,3-A]Pyridin-8- Yl)Propan-2-Ol
Organism: Mus musculus
Method: X-RAY DIFFRACTION Resolution:2.65 Å Release Date: 2018-12-19 Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR Ligands: NAP, HJG, SO4 |
Organism: Mus musculus
Method: X-RAY DIFFRACTION
Release Date: 2018-12-19
Ligands: NAP, HJG, SO4
 |
Crystal Structure Of 11Beta-Hsd1 Double Mutant (L262R, F278E) Complexed With 2-[2-(4-Fluorophenyl)-2-Adamantyl]-1-(3-Methoxyazetidin-1-Yl)Ethanone
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.35 Å Release Date: 2017-11-01 Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR Ligands: NAP, 8K4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-11-01
Ligands: NAP, 8K4
 |
Crystal Structure Of 11Beta-Hsd1 Double Mutant (L262R, F278E) Complexed With 1-(3-Hydroxyazetidin-1-Yl)-2-[(2S,5R)-2-(4-Fluorophenyl)-5-Methoxyadamantan-2-Yl]Ethan-1-One
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.35 Å Release Date: 2017-11-01 Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR Ligands: NAP, 8K7 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-11-01
Ligands: NAP, 8K7
 |
Crystal Structure Of 11Beta-Hsd1 Double Mutant (L262R, F278E) Complexed With 2-[(1R,3S,5R,7S)-2-[4-(4-Fluorophenyl)Phenyl]-6-Hydroxyadamantan-2-Yl]-1-(3- Hydroxyazetidin-1-Yl)Ethan-1-One
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.37 Å Release Date: 2017-11-01 Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR Ligands: NAP, 8KA |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-11-01
Ligands: NAP, 8KA
 |
Crystal Structure Of 11Beta-Hsd1 Double Mutant (L262R, F278E) Complexed With 2-(2-Benzyl-6-Hydroxyadamantan-2-Yl)-1-(3-Hydroxyazetidin-1-Yl)Ethan-1-One
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.50 Å Release Date: 2017-11-01 Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR Ligands: NAP, 8KD |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-11-01
Ligands: NAP, 8KD
 |
Crystal Structure Of 11Beta-Hsd1 Double Mutant (L262R, F278E) Complexed With 2-[(5R,7S)-6-Hydroxy-2-Phenyladamantan-2-Yl]-1-(3-Hydroxyazetidin-1-Yl)Ethan-1-One (Bms-816336)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.07 Å Release Date: 2017-11-01 Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR Ligands: NAP, 8KG |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-11-01
Ligands: NAP, 8KG
 |
Crystal Structure Of Murine 11Beta- Hydroxysteroiddehydrogenase Complexed With 2-[(5R,7S)-6-Hydroxy-2-Phenyladamantan-2-Yl]-1-(3-Hydroxyazetidin-1-Yl)Ethan-1-One (Bms-816336)
Organism: Mus musculus
Method: X-RAY DIFFRACTION Resolution:2.90 Å Release Date: 2017-11-01 Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR Ligands: NAP, 8KG, SO4 |
Organism: Mus musculus
Method: X-RAY DIFFRACTION
Release Date: 2017-11-01
Ligands: NAP, 8KG, SO4
 |
Factor Xia In Complex With The Inhibitor 4-[(N-{(2E)-3-[5-Chloro-2-(1H-Tetrazol-1-Yl)Phenyl]Prop-2-Enoyl}-L-Phenylalanyl)Amino]Benzoic Acid
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.08 Å Release Date: 2015-12-09 Classification: Hydrolase/Hydrolase Inhibitor Ligands: 5JM, SO4, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-12-09
Ligands: 5JM, SO4, EDO
 |
Factor Xia In Complex With The Inhibitor N-[(1S)-1-Benzyl-2-[2-[5-Chloro-2-(Tetrazol-1-Yl)Phenyl]Ethylamino]-2-Oxo-Ethyl]-4-Hydroxy-2-Oxo-1H-Quinoline-6-Carboxamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.11 Å Release Date: 2015-12-09 Classification: Hydrolase/Hydrolase Inhibitor Ligands: 7P0, SO4, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-12-09
Ligands: 7P0, SO4, EDO
 |
Factor Viia In Complex With The Inhibitor 4-Bromo-2-Methoxyphenol
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.10 Å Release Date: 2015-03-25 Classification: hydrolase/hydrolase inhibitor Ligands: 3Z7, CA, SO4, GOL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-03-25
Ligands: 3Z7, CA, SO4, GOL
 |
Factor Viia In Complex With The Inhibitor 7-Chloro-3,4-Dihydroisoquinolin-1(2H)-One
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.20 Å Release Date: 2015-03-25 Classification: hydrolase/hydrolase inhibitor Ligands: 3Z8, CA, SO4, GOL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-03-25
Ligands: 3Z8, CA, SO4, GOL
 |
Factor Viia In Complex With The Inhibitor 5-Chloro-1H-Indole-2-Carboxylic Acid
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.10 Å Release Date: 2015-03-25 Classification: hydrolase/hydrolase inhibitor Ligands: 3ZB, CA, SO4, GOL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-03-25
Ligands: 3ZB, CA, SO4, GOL
 |
Factor Viia In Complex With The Inhibitor (Methyl {3-[(2R)-1-{(2R)-2-(3,4-Dimethoxyphenyl)-2-[(1-Oxo-1,2,3,4-Tetrahydroisoquinolin-7-Yl)Amino]Acetyl}Pyrrolidin-2-Yl]-4-(Propan-2-Ylsulfonyl)Phenyl}Carbamate)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.50 Å Release Date: 2015-03-25 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: 3Z9, CA, SO4, GOL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-03-25
Ligands: 3Z9, CA, SO4, GOL
 |
Factor Xia In Complex With The Inhibitor 1-{(1S)-1-[4-(3-Amino-1H-Indazol-6-Yl)-5-Chloro-1H-Imidazol-2-Yl]-2-Phenylethyl}-3-[2-(Aminomethyl)-5-Chlorobenzyl]Urea
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.40 Å Release Date: 2015-02-18 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: 3Y3, SO4, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-02-18
Ligands: 3Y3, SO4, EDO
 |
Factor Xia In Complex With The Inhibitor 1-{(1S)-1-[4-(3-Amino-1H-Indazol-6-Yl)-5-Chloro-1H-Imidazol-2-Yl]-2-Phenylethyl}-3-[5-Chloro-2-(1H-Tetrazol-1-Yl)Benzyl]Urea
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.10 Å Release Date: 2015-02-18 Classification: hydrolase/hydrolase inhibitor Ligands: 3Y5, SO4, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-02-18
Ligands: 3Y5, SO4, EDO
 |
Factor Xia In Complex With The Inhibitor Methyl (4-{4-Chloro-2-[(1S)-1-({3-[5-Chloro-2-(1H-Tetrazol-1-Yl)Phenyl]Propanoyl}Amino)-2-Phenylethyl]-1H-Imidazol-5-Yl}Phenyl)Carbamate
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.10 Å Release Date: 2015-02-18 Classification: hydrolase/hydrolase inhibitor Ligands: 3Y4, SO4, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-02-18
Ligands: 3Y4, SO4, EDO
 |
Factor Xia (Pichia Pastoris; C500S [C122S]) In Complex With The Inhibitor (2E)-N-{(1S)-1-[4-(3-Amino-1H-Indazol-6-Yl)-1H-Imidazol-2-Yl]-2-Phenylethyl}-3-[5-Chloro-2-(1H-Tetrazol-1-Yl)Phenyl]Prop-2-Enamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.93 Å Release Date: 2015-02-18 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: NAG, 3YU, CIT, GOL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-02-18
Ligands: NAG, 3YU, CIT, GOL
 |
Factor Xia In Complex With The Inhibitor Trans-N-{(1S)-1-[4-(3-Amino-2H-Indazol-6-Yl)Pyridin-2-Yl]-2-Phenylethyl}-4-(Aminomethyl)Cyclohexanecarboxamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.60 Å Release Date: 2015-01-28 Classification: hydrolase/hydrolase inhibitor Ligands: 3VM, SO4, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-01-28
Ligands: 3VM, SO4, EDO
 |
Factor Xia In Complex With The Inhibitor 4-{2-[(1S)-1-({[Trans-4-(Aminomethyl)Cyclohexyl]Carbonyl}Amino)-2-Phenylethyl]-1H-Imidazol-4-Yl}Benzamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.85 Å Release Date: 2014-12-03 Classification: Hydrolase/Hydrolase Inhibitor Ligands: 39D, SO4, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-12-03
Ligands: 39D, SO4, EDO