Search Count: 48
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Structure Of Kras-G12C Bound To 1-[(4Ar,10P,13R)-10-[5-Amino-4-Fluoro-3-Methyl-2-(Trifluoromethyl)Phenyl]-11-Chloro-9-Fluoro-1,2,4A,5-Tetrahydropyrazino[1',2':4,5][1,4]Oxazino[2,3-C]Quinolin-3(4H)-Yl]Prop-2-En-1-One (Compound 15)
Organism: Homo sapiens, Synthetic construct
Method: X-RAY DIFFRACTION Resolution:1.94 Å Release Date: 2026-03-11 Classification: ONCOPROTEIN Ligands: MG, GDP, A1CII, PEG, GOL, DMS, ACT |
Organism: Homo sapiens, Synthetic construct
Method: X-RAY DIFFRACTION
Release Date: 2026-03-11
Ligands: MG, GDP, A1CII, PEG, GOL, DMS, ACT
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Structure Of Kras G12C Bound To Compound 4
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.84 Å Release Date: 2026-03-11 Classification: ONCOPROTEIN Ligands: A1CQ2, GDP, MG |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2026-03-11
Ligands: A1CQ2, GDP, MG
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Structure Of Kras G12C Bound To Divarasib (Gdc6036)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.17 Å Release Date: 2026-03-11 Classification: ONCOPROTEIN Ligands: GDP, MG, DMS, EDO, A1AWR, PEG |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2026-03-11
Ligands: GDP, MG, DMS, EDO, A1AWR, PEG
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Brg1 Bromodomain In Complex With Vbc Via Compound 17
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:3.17 Å Release Date: 2024-01-17 Classification: GENE REGULATION Ligands: PO4, GOL, VLH, CL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-01-17
Ligands: PO4, GOL, VLH, CL
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Vhl/Elongin B/Elongin C Complex With Compound 155
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:3.19 Å Release Date: 2024-01-17 Classification: LIGASE Ligands: VL6 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-01-17
Ligands: VL6
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Brm (Smarca2) Bromodomain In Complex With Ligand 10
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.57 Å Release Date: 2024-01-17 Classification: GENE REGULATION Ligands: ZN, VLC, CL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-01-17
Ligands: ZN, VLC, CL
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Identification Of Gdc-1971 (Rly-1971), A Shp2 Inhibitor Designed For The Treatment Of Solid Tumors
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.40 Å Release Date: 2023-10-11 Classification: HYDROLASE Ligands: SO4, YR2 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2023-10-11
Ligands: SO4, YR2
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Identification Of Gdc-1971 (Rly-1971), A Shp2 Inhibitor Designed For The Treatment Of Solid Tumors
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.84 Å Release Date: 2023-10-11 Classification: HYDROLASE Ligands: SO4, YT2 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2023-10-11
Ligands: SO4, YT2
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Identification Of Gdc-1971 (Rly-1971), A Shp2 Inhibitor Designed For The Treatment Of Solid Tumors
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.10 Å Release Date: 2023-10-11 Classification: HYDROLASE Ligands: ZH5 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2023-10-11
Ligands: ZH5
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Identification Of Gdc-1971 (Rly-1971), A Shp2 Inhibitor Designed For The Treatment Of Solid Tumors
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.27 Å Release Date: 2023-10-11 Classification: HYDROLASE/INHIBITOR Ligands: ZJX |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2023-10-11
Ligands: ZJX
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Kras G12C In Complex With G-2897
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.96 Å Release Date: 2022-03-16 Classification: HYDROLASE/Immune System Ligands: Z07, GDP, MG, ACT, CAD, P15, EDO, DMS |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2022-03-16
Ligands: Z07, GDP, MG, ACT, CAD, P15, EDO, DMS
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Crystal Structure Of Kas G12C In Complex With 2H11 Clamp
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.20 Å Release Date: 2022-03-16 Classification: Hydrolase/Immune System Ligands: GDP, MG, CAC, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2022-03-16
Ligands: GDP, MG, CAC, EDO
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Crystal Structure Of Gne-1952 Alkylated Kras G12C In Complex With 2H11 Clamp
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.00 Å Release Date: 2022-03-16 Classification: Hydrolase/Immune System Ligands: MKZ, GDP, MG, GOL, EDO, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2022-03-16
Ligands: MKZ, GDP, MG, GOL, EDO, SO4
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Crystal Structure Of Kras G12C In Complex With Gne-1952
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.15 Å Release Date: 2022-03-16 Classification: HYDROLASE Ligands: MKZ, GDP, MG, GOL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2022-03-16
Ligands: MKZ, GDP, MG, GOL
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Envelope Glycprotein Of Endogenous Retrovirus Y032 (Atlas Virus) From The Human Hookworm Ancylostoma Ceylanicum
Organism: Ancylostoma ceylanicum
Method: ELECTRON MICROSCOPY Release Date: 2021-09-01 Classification: VIRAL PROTEIN Ligands: NAG |
Organism: Ancylostoma ceylanicum
Method: ELECTRON MICROSCOPY
Release Date: 2021-09-01
Ligands: NAG
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Crystal Structure Of Braf In Complex With Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.49 Å Release Date: 2021-05-26 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: V5J, IOD |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2021-05-26
Ligands: V5J, IOD
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Crystal Structure Of Braf In Complex With Inhibitor Gne-0749
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.93 Å Release Date: 2021-05-26 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: VQP, CL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2021-05-26
Ligands: VQP, CL
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Crystal Structure Of Ire1A In Complex With Compound 18
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.20 Å Release Date: 2019-11-06 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: QFV, GOL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2019-11-06
Ligands: QFV, GOL
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Crebbp Bromodomain In Complex With Cpd3 ((S)-1-(3-(6-(1-Methyl-1H-Pyrazol-4-Yl)-3,4-Dihydroquinolin-1(2H)-Yl)-1-(Tetrahydrofuran-3-Yl)-1,4,6,7-Tetrahydro-5H-Pyrazolo[4,3-C]Pyridin-5-Yl)Ethan-1-One)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.60 Å Release Date: 2018-03-07 Classification: TRANSCRIPTION REGULATOR/INHIBITOR Ligands: 9U7 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2018-03-07
Ligands: 9U7
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Crebbp Bromodomain In Complex With Cpd8 (1-(3-(7-(Difluoromethyl)-6-(1-Methyl-1H-Pyrazol-4-Yl)-3,4-Dihydroquinolin-1(2H)-Yl)-1-(Tetrahydrofuran-3-Yl)-1,4,6,7-Tetrahydro-5H-Pyrazolo[4,3-C]Pyridin-5-Yl)Ethan-1-One)
Organism: Mus musculus
Method: X-RAY DIFFRACTION Resolution:1.43 Å Release Date: 2018-03-07 Classification: TRANSFERASE/INHIBITOR Ligands: 9UA, DMS, GOL |
Organism: Mus musculus
Method: X-RAY DIFFRACTION
Release Date: 2018-03-07
Ligands: 9UA, DMS, GOL