Search Count: 21
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Human Prmt5:Mep50 In Complex With Azd3470
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.18 Å Release Date: 2026-06-10 Classification: TRANSFERASE Ligands: A1JTI, MTA, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2026-06-10
Ligands: A1JTI, MTA, SO4
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Crystal Structure Of Cdk2 Bound By Compound 4
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.16 Å Release Date: 2025-09-10 Classification: TRANSFERASE Ligands: A1INI |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-09-10
Ligands: A1INI
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Crystal Structure Of Cdk2-Cyclin E1 Bound By Compound 30
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.16 Å Release Date: 2025-09-10 Classification: TRANSFERASE Ligands: A1IOI |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-09-10
Ligands: A1IOI
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Crystal Structure Of Cdk2-Cyclin E1 Bound By Compound 11 (Azd8421)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.45 Å Release Date: 2025-09-10 Classification: TRANSFERASE Ligands: A1IOP |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-09-10
Ligands: A1IOP
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Crystal Structure Of Parp1 Catalytic Domain Bound To Azd5305 (Saruparib)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.59 Å Release Date: 2024-12-04 Classification: TRANSFERASE Ligands: A1H63, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-12-04
Ligands: A1H63, SO4
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Crystal Structure Of Parp1 Catalytic Domain Bound To Azd9574
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.82 Å Release Date: 2024-12-04 Classification: TRANSFERASE Ligands: A1H64, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-12-04
Ligands: A1H64, SO4
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Optimisation Of Potent, Efficacious, Selective And Blood-Brain Barrier Penetrating Inhibitors Targeting Egfr Exon20 Insertion Mutations
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.44 Å Release Date: 2024-11-06 Classification: SIGNALING PROTEIN Ligands: A1H7N, IOD |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-11-06
Ligands: A1H7N, IOD
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Optimisation Of Potent, Efficacious, Selective And Blood-Brain Barrier Penetrating Inhibitors Targeting Egfr Exon20 Insertion Mutations
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:3.02 Å Release Date: 2024-10-16 Classification: SIGNALING PROTEIN Ligands: A1H7O |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-10-16
Ligands: A1H7O
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Human Prmt5 In Complex With Az Compound 1
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.35 Å Release Date: 2024-08-14 Classification: TRANSFERASE Ligands: A1H8A, MTA, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-08-14
Ligands: A1H8A, MTA, SO4
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Human Prmt5 In Complex With Az Compound 12
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.15 Å Release Date: 2024-08-14 Classification: TRANSFERASE Ligands: A1H76, MTA, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-08-14
Ligands: A1H76, MTA, SO4
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Human Prmt5 In Complex With Az Compound 21
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.30 Å Release Date: 2024-08-14 Classification: TRANSFERASE Ligands: A1H8B, MTA, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-08-14
Ligands: A1H8B, MTA, SO4
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Human Prmt5 In Complex With Az Compound 28
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.20 Å Release Date: 2024-08-14 Classification: TRANSFERASE Ligands: A1H73, MTA, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-08-14
Ligands: A1H73, MTA, SO4
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Discovery And Optimisation Of Potent, Efficacious And Selective Inhibitors Targeting Egfr Exon20 Insertion Mutations. Compound 16 Bound To Egfr
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.51 Å Release Date: 2024-06-05 Classification: SIGNALING PROTEIN Ligands: 2I0 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-06-05
Ligands: 2I0
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Discovery And Optimisation Of Potent, Efficacious And Selective Inhibitors Targeting Egfr Exon20 Insertion Mutations. Compound 12 Bound To Egfrinsnpg
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.52 Å Release Date: 2024-06-05 Classification: SIGNALING PROTEIN Ligands: 2I6 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-06-05
Ligands: 2I6
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Discovery And Optimisation Of Potent, Efficacious And Selective Inhibitors Targeting Egfr Exon20 Insertion Mutations. Compound 22 Bound To Egfrinsnpg [V948R]
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.11 Å Release Date: 2024-06-05 Classification: SIGNALING PROTEIN Ligands: 2EI, IOD |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-06-05
Ligands: 2EI, IOD
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Discovery And Optimisation Of Potent, Efficacious And Selective Inhibitors Targeting Egfr Exon20 Insertion Mutations. Compound 33 Bound To Egfrinsnpg [V948R]
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.28 Å Release Date: 2024-06-05 Classification: SIGNALING PROTEIN Ligands: 26X |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-06-05
Ligands: 26X
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Discovery And Optimisation Of Potent, Efficacious And Selective Inhibitors Targeting Egfr Exon20 Insertion Mutations. Compound 18 Bound To Egfr[V948R]
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.13 Å Release Date: 2024-06-05 Classification: SIGNALING PROTEIN Ligands: 2II |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-06-05
Ligands: 2II
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Discovery And Optimisation Of Potent, Efficacious And Selective Inhibitors Targeting Egfr Exon20 Insertion Mutations. Compound 33 Bound To Egfr[V948R]
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.62 Å Release Date: 2024-06-05 Classification: SIGNALING PROTEIN Ligands: 26X, ATP, MG |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-06-05
Ligands: 26X, ATP, MG
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Parp1 Catalytic Domain In Complex With 8-Chloroquinazolinone-Based Inhibitor (Compound 9)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.05 Å Release Date: 2021-09-15 Classification: TRANSFERASE Ligands: VKW, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2021-09-15
Ligands: VKW, SO4
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Parp1 Catalytic Domain In Complex With Isoquinolone-Based Inhibitor (Compound 16)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.97 Å Release Date: 2021-09-15 Classification: TRANSFERASE Ligands: VKT, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2021-09-15
Ligands: VKT, SO4