Search Count: 63
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Structure Of Kras-G12C Bound To 1-[(4Ar,10P,13R)-10-[5-Amino-4-Fluoro-3-Methyl-2-(Trifluoromethyl)Phenyl]-11-Chloro-9-Fluoro-1,2,4A,5-Tetrahydropyrazino[1',2':4,5][1,4]Oxazino[2,3-C]Quinolin-3(4H)-Yl]Prop-2-En-1-One (Compound 15)
Organism: Homo sapiens, Synthetic construct
Method: X-RAY DIFFRACTION Resolution:1.94 Å Release Date: 2026-03-11 Classification: ONCOPROTEIN Ligands: MG, GDP, A1CII, PEG, GOL, DMS, ACT |
Organism: Homo sapiens, Synthetic construct
Method: X-RAY DIFFRACTION
Release Date: 2026-03-11
Ligands: MG, GDP, A1CII, PEG, GOL, DMS, ACT
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Structure Of Kras G12C Bound To Compound 4
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.84 Å Release Date: 2026-03-11 Classification: ONCOPROTEIN Ligands: A1CQ2, GDP, MG |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2026-03-11
Ligands: A1CQ2, GDP, MG
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Structure Of Kras G12C Bound To Divarasib (Gdc6036)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.17 Å Release Date: 2026-03-11 Classification: ONCOPROTEIN Ligands: GDP, MG, DMS, EDO, A1AWR, PEG |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2026-03-11
Ligands: GDP, MG, DMS, EDO, A1AWR, PEG
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Crystal Structure Of Inhibitor Gne-6893 Bound To Hpk1
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.25 Å Release Date: 2024-10-02 Classification: SIGNALING PROTEIN Ligands: A1APL, DMS, NA |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-10-02
Ligands: A1APL, DMS, NA
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Crystal Structure Of Inhibitor 1 Bound To Hpk1
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.25 Å Release Date: 2024-10-02 Classification: SIGNALING PROTEIN Ligands: EDO, A1APO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-10-02
Ligands: EDO, A1APO
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Crystal Structure Of Inhibitor Gne-6893 Bound To Hpk1
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.18 Å Release Date: 2024-10-02 Classification: SIGNALING PROTEIN Ligands: MES, EDO, DMS, A1APR, NA, PEG, A1APQ |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-10-02
Ligands: MES, EDO, DMS, A1APR, NA, PEG, A1APQ
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Kras-G13D-Gdp In Complex With Cpd5 (1-((S)-10-(6-Amino-4-Methyl-3-(Trifluoromethyl)Pyridin-2-Yl)-11-Chloro-7-(((2S,4R)-4-Fluoro-1-Methylpyrrolidin-2-Yl)Methoxy)-3,4,13,13A-Tetrahydropyrazino[2',1':3,4][1,4]Oxazepino[5,6,7-De]Quinazolin-2(1H)-Yl)Prop-2-En-1-One)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.07 Å Release Date: 2023-12-20 Classification: HYDROLASE,ONCOPROTEIN/INHIBITOR Ligands: XOI, GDP, CL, MG, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2023-12-20
Ligands: XOI, GDP, CL, MG, EDO
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Kras-G13D-Gdp In Complex With Cpd36 ((E)-1-((3S)-4-(7-(6-Amino-4-Methyl-3-(Trifluoromethyl)Pyridin-2-Yl)-6-Chloro-8-Fluoro-2-(((S)-2-Methylenetetrahydro-1H-Pyrrolizin-7A(5H)-Yl)Methoxy)Quinazolin-4-Yl)-3-Methylpiperazin-1-Yl)-3-(4-((Dimethylamino)Methyl)-5-Methylpyridin-2-Yl)Prop-2-En-1-One)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.57 Å Release Date: 2023-12-20 Classification: HYDROLASE,ONCOPROTEIN/INHIBITOR Ligands: MG, GDP, XV3 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2023-12-20
Ligands: MG, GDP, XV3
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Kras-G13D-Gdp In Complex With Cpd38 ((E)-1-((3S)-4-(7-(6-Amino-4-Methyl-3-(Trifluoromethyl)Pyridin-2-Yl)-6-Chloro-8-Fluoro-2-(((S)-2-Methylenetetrahydro-1H-Pyrrolizin-7A(5H)-Yl)Methoxy)Quinazolin-4-Yl)-3-Methylpiperazin-1-Yl)-3-(1,2,3,4-Tetrahydroisoquinolin-8-Yl)Prop-2-En-1-One)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.31 Å Release Date: 2023-12-20 Classification: HYDROLASE,ONCOPROTEIN/INHIBITOR Ligands: GOL, GDP, MG, XQ6 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2023-12-20
Ligands: GOL, GDP, MG, XQ6
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Kras G12C In Complex With G-2897
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.96 Å Release Date: 2022-03-16 Classification: HYDROLASE/Immune System Ligands: Z07, GDP, MG, ACT, CAD, P15, EDO, DMS |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2022-03-16
Ligands: Z07, GDP, MG, ACT, CAD, P15, EDO, DMS
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Crystal Structure Of Kas G12C In Complex With 2H11 Clamp
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.20 Å Release Date: 2022-03-16 Classification: Hydrolase/Immune System Ligands: GDP, MG, CAC, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2022-03-16
Ligands: GDP, MG, CAC, EDO
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Crystal Structure Of Gne-1952 Alkylated Kras G12C In Complex With 2H11 Clamp
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.00 Å Release Date: 2022-03-16 Classification: Hydrolase/Immune System Ligands: MKZ, GDP, MG, GOL, EDO, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2022-03-16
Ligands: MKZ, GDP, MG, GOL, EDO, SO4
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Crystal Structure Of Kras G12C In Complex With Gne-1952
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.15 Å Release Date: 2022-03-16 Classification: HYDROLASE Ligands: MKZ, GDP, MG, GOL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2022-03-16
Ligands: MKZ, GDP, MG, GOL
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The Pore Conformation Of Lymphocyte Perforin
Organism: Mus musculus
Method: ELECTRON MICROSCOPY Release Date: 2022-02-16 Classification: IMMUNE SYSTEM Ligands: CA, NAG |
Organism: Mus musculus
Method: ELECTRON MICROSCOPY
Release Date: 2022-02-16
Ligands: CA, NAG
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Crystal Structure Of Hpk1 In Complex With Compound 2
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.33 Å Release Date: 2022-01-05 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 2YE |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2022-01-05
Ligands: 2YE
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Crystal Structure Of Hpk1 In Complex With Gne1858
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.50 Å Release Date: 2022-01-05 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: F97, EDO, MES |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2022-01-05
Ligands: F97, EDO, MES
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Crystal Structure Of Hpk1 In Complex With Compound 14
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.27 Å Release Date: 2022-01-05 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 2WI, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2022-01-05
Ligands: 2WI, SO4
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Crystal Structure Of Hpk1 In Complex With Compound 17
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.00 Å Release Date: 2022-01-05 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 2TR |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2022-01-05
Ligands: 2TR
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Crystal Structure Of Trmd, A Trna-(N1G37) Methyltransferase, From Mycobacterium Abscessus In Complex With Inhibitor
Organism: Mycobacterium abscessus
Method: X-RAY DIFFRACTION Resolution:1.76 Å Release Date: 2020-03-18 Classification: TRANSFERASE Ligands: JCZ |
Organism: Mycobacterium abscessus
Method: X-RAY DIFFRACTION
Release Date: 2020-03-18
Ligands: JCZ
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Crystal Structure Of Trmd, A Trna-(N1G37) Methyltransferase, From Mycobacterium Abscessus In Complex With Inhibitor
Organism: Mycobacterium abscessus
Method: X-RAY DIFFRACTION Resolution:2.69 Å Release Date: 2020-03-18 Classification: TRANSFERASE Ligands: JCE, SO4 |
Organism: Mycobacterium abscessus
Method: X-RAY DIFFRACTION
Release Date: 2020-03-18
Ligands: JCE, SO4