Search Count: 23
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Design And Application Of Synthetic 17B-Hsd13 Substrates To Drug Discovery, And To Reveal Preserved Catalytic Activity Of Protective Human Variants
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.09 Å Release Date: 2024-11-27 Classification: HYDROLASE Ligands: NAD, A1AG4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-11-27
Ligands: NAD, A1AG4
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Design And Application Of Synthetic 17B-Hsd13 Substrates To Drug Discovery, And To Reveal Preserved Catalytic Activity Of Protective Human Variants
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.36 Å Release Date: 2024-11-27 Classification: HYDROLASE Ligands: NAD, A1AG5 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-11-27
Ligands: NAD, A1AG5
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Design And Application Of Synthetic 17B-Hsd13 Substrates To Drug Discovery, And To Reveal Preserved Catalytic Activity Of Protective Human Variants
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.59 Å Release Date: 2024-11-27 Classification: HYDROLASE Ligands: NAD, A1AG6 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-11-27
Ligands: NAD, A1AG6
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Bruton'S Tyrosine Kinase In Complex With Covalent Inhibitor Compound 10
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.70 Å Release Date: 2024-06-26 Classification: TRANSFERASE/INHIBITOR Ligands: UEO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-06-26
Ligands: UEO
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Bruton'S Tyrosine Kinase In Complex With Covalent Inhibitor Compound 25
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.60 Å Release Date: 2024-06-26 Classification: TRANSFERASE/INHIBITOR Ligands: V72 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-06-26
Ligands: V72
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Bruton'S Tyrosine Kinase In Complex With Covalent Inhibitor Compound 27
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.10 Å Release Date: 2024-06-26 Classification: TRANSFERASE/INHIBITOR Ligands: V7I |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-06-26
Ligands: V7I
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Bruton'S Tyrosine Kinase In Complex With Compound 23
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.69 Å Release Date: 2022-01-12 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: YD7, DMS |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2022-01-12
Ligands: YD7, DMS
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Bruton'S Tyrosine Kinase In Complex With Compound 51
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.53 Å Release Date: 2022-01-12 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: YDA, DTT, ACT |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2022-01-12
Ligands: YDA, DTT, ACT
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Structure Of Khk In Complex With Compound 2
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.41 Å Release Date: 2020-09-23 Classification: TRANSFERASE Ligands: RYS, SO4, CIT |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-09-23
Ligands: RYS, SO4, CIT
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Structure Of Khk In Complex With Compound 3
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.80 Å Release Date: 2020-09-23 Classification: TRANSFERASE Ligands: RZA, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-09-23
Ligands: RZA, SO4
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Structure Of Khk In Complex With Compound 4 (6-[(1~{S},5~{R})-6-(Hydroxymethyl)-3-Azabicyclo[3.1.0]Hexan-3-Yl]-2-[(2~{S},3~{R})-2-Methyl-3-Oxidanyl-Azetidin-1-Yl]-4-(Trifluoromethyl)Pyridine-3-Carbonitrile)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.38 Å Release Date: 2020-09-23 Classification: TRANSFERASE Ligands: S6J, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-09-23
Ligands: S6J, SO4
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Structure Of Khk In Complex With Compound 6 (2-[(1~{R},5~{S})-3-[5-Cyano-6-[(2~{S},3~{R})-2-Methyl-3-Oxidanyl-Azetidin-1-Yl]-4-(Trifluoromethyl)Pyridin-2-Yl]-3-Azabicyclo[3.1.0]Hexan-6-Yl]Ethanoic Acid)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.54 Å Release Date: 2020-09-23 Classification: TRANSFERASE Ligands: S6S, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-09-23
Ligands: S6S, SO4
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Structure Of Khk In Complex With Compound 8 (2-[(1~{S},5~{R})-3-[2-[(2~{S})-2-Methylazetidin-1-Yl]-6-(Trifluoromethyl)Pyrimidin-4-Yl]-3-Azabicyclo[3.1.0]Hexan-6-Yl]Ethanoic Acid)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.30 Å Release Date: 2020-09-23 Classification: TRANSFERASE Ligands: S6D, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-09-23
Ligands: S6D, SO4
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Structure Of Human Ketohexokinase Complexed With Hits From Fragment Screening
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.16 Å Release Date: 2017-09-13 Classification: TRANSFERASE Ligands: A4G, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-09-13
Ligands: A4G, SO4
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Structure Of Human Ketohexokinase Complexed With Hits From Fragment Screening
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.25 Å Release Date: 2017-09-13 Classification: TRANSFERASE Ligands: A1Y, SO4, CIT, GOL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-09-13
Ligands: A1Y, SO4, CIT, GOL
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Structure Of Human Ketohexokinase Complexed With Hits From Fragment Screening
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.74 Å Release Date: 2017-09-13 Classification: TRANSFERASE Ligands: A2J, SO4, GOL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-09-13
Ligands: A2J, SO4, GOL
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Structure Of Human Ketohexokinase Complexed With Hits From Fragment Screening
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.40 Å Release Date: 2017-09-13 Classification: TRANSFERASE Ligands: A3J, SO4, CL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-09-13
Ligands: A3J, SO4, CL
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Structure Of Human Ketohexokinase Complexed With Hits From Fragment Screening
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.58 Å Release Date: 2017-09-13 Classification: TRANSFERASE Ligands: A3Y, SO4, CIT, GOL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-09-13
Ligands: A3Y, SO4, CIT, GOL
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Structure Of Human Ketohexokinase Complexed With Hits From Fragment Screening
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.40 Å Release Date: 2017-09-13 Classification: TRANSFERASE Ligands: A4J, SO4, CIT |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-09-13
Ligands: A4J, SO4, CIT
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Covalent Inhibitor Of Lyplal1
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.00 Å Release Date: 2016-07-20 Classification: HYDROLASE/HYDROLASE inhibitor Ligands: 6WG, NO3 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-07-20
Ligands: 6WG, NO3