Search Count: 19
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Plasmodium Falciparum Dihydroorotate Dehydrogenase In Complex With 3-Hydroxy-1-Methyl Pyrazole Derivatives
Organism: Plasmodium falciparum
Method: X-RAY DIFFRACTION Resolution:2.95 Å Release Date: 2026-04-01 Classification: OXIDOREDUCTASE Ligands: FMN, ORO, A1JWR |
Organism: Plasmodium falciparum
Method: X-RAY DIFFRACTION
Release Date: 2026-04-01
Ligands: FMN, ORO, A1JWR
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Plasmodium Falciparum Dihydroorotate Dehydrogenase In Complex With 3-Hydroxy-1-Methyl Pyrazole Derivatives
Organism: Plasmodium falciparum
Method: X-RAY DIFFRACTION Resolution:2.40 Å Release Date: 2026-04-01 Classification: OXIDOREDUCTASE Ligands: FMN, ORO, A1JWQ |
Organism: Plasmodium falciparum
Method: X-RAY DIFFRACTION
Release Date: 2026-04-01
Ligands: FMN, ORO, A1JWQ
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Crystal Structure Of Human Dihydroorotate Dehydrogenase In Complex With Arzanol
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.61 Å Release Date: 2025-11-12 Classification: OXIDOREDUCTASE Ligands: FMN, ORO, A1JKW, ACT, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-11-12
Ligands: FMN, ORO, A1JKW, ACT, SO4
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Structure Of Aldo-Keto Reductase 1C3 (Akr1C3) In Complex With An Inhibitor Meds765
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.75 Å Release Date: 2024-08-21 Classification: OXIDOREDUCTASE Ligands: NAP, A1ICG, EDO, MES |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-08-21
Ligands: NAP, A1ICG, EDO, MES
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Crystal Structure Of Human Dihydroorotate Dehydrogenase In Complex With The Inhibitor 2-Hydroxy-N-(2-Isopropyl-5-Methyl-4-(Pyridin-4-Yloxy)Phenyl)Pyrazolo[1,5-A]Pyridine-3-Carboxamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.85 Å Release Date: 2024-06-19 Classification: FLAVOPROTEIN Ligands: FMN, ORO, YMH, ACT, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-06-19
Ligands: FMN, ORO, YMH, ACT, SO4
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Structure Of Aldo-Keto Reductase 1C3 (Akr1C3) In Complex With An Inhibitor M689, With The 3-Hydroxy-Benzoisoxazole Moiety. Resolution 2.0A
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.00 Å Release Date: 2024-03-06 Classification: OXIDOREDUCTASE Ligands: NAP, YMC, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-03-06
Ligands: NAP, YMC, EDO
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Crystal Structure Of The Full-Length Dihydroorotate Dehydrogenase From Mycobacterium Tuberculosis
Organism: Mycobacterium tuberculosis
Method: X-RAY DIFFRACTION Resolution:3.80 Å Release Date: 2023-09-06 Classification: OXIDOREDUCTASE Ligands: FMN |
Organism: Mycobacterium tuberculosis
Method: X-RAY DIFFRACTION
Release Date: 2023-09-06
Ligands: FMN
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Crystal Structure Of Human Dihydroorotate Dehydrogenase In Complex With The Inhibitor 2-Hydroxy-N-(2-Ispropyl-5-Methyl-4-Phenoxyphenyl)Pyrazolo[1,5-A]Pyridine-3-Carboxamide.
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.85 Å Release Date: 2022-10-12 Classification: OXIDOREDUCTASE Ligands: FMN, ORO, IEQ, P6G, ACT |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2022-10-12
Ligands: FMN, ORO, IEQ, P6G, ACT
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Crystal Structure Of Aldo-Keto Reductase 1C3 (Akr1C3) Complexed With Inhibitor.
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.70 Å Release Date: 2019-05-08 Classification: OXIDOREDUCTASE Ligands: NAP, FFW, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2019-05-08
Ligands: NAP, FFW, EDO
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Structure Of Glua2 Ligand-Binding Domain (S1S2J) In Complex With The Agonist (S)-2-Amino-3-(1-Ethyl-4-Hydroxy-1H-1,2,3-Triazol-5-Yl)Propanoic Acid At 1.4 A Resolution
Organism: Rattus norvegicus
Method: X-RAY DIFFRACTION Resolution:1.40 Å Release Date: 2019-04-17 Classification: MEMBRANE PROTEIN Ligands: SO4, HJ8, GOL, PGE, CL, CIT, LI, PEG |
Organism: Rattus norvegicus
Method: X-RAY DIFFRACTION
Release Date: 2019-04-17
Ligands: SO4, HJ8, GOL, PGE, CL, CIT, LI, PEG
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Structure Of Glua2 Ligand-Binding Domain (S1S2J) In Complex With The Agonist (S)-2-Amino-3-(2-Methyl-5-Hydroxy-2H-1,2,3-Triazol-4-Yl)Propanoic Acid At 1.55 A Resolution
Organism: Rattus norvegicus
Method: X-RAY DIFFRACTION Resolution:1.55 Å Release Date: 2019-04-17 Classification: MEMBRANE PROTEIN Ligands: HJH, SO4, GOL, CL, LI |
Organism: Rattus norvegicus
Method: X-RAY DIFFRACTION
Release Date: 2019-04-17
Ligands: HJH, SO4, GOL, CL, LI
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Plasmodium Falciparum Dihydroorotate Dehydrogenase (Dhodh) Co-Crystallized With 3-Hydroxy-1-Methyl-5-((3-(Trifluoromethyl)Phenoxy)Methyl)-1H-Pyrazole-4-Carboxylic Acid
Organism: Plasmodium falciparum
Method: X-RAY DIFFRACTION Resolution:1.98 Å Release Date: 2018-12-19 Classification: OXIDOREDUCTASE Ligands: FMN, ORO, E2N |
Organism: Plasmodium falciparum
Method: X-RAY DIFFRACTION
Release Date: 2018-12-19
Ligands: FMN, ORO, E2N
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Plasmodium Falciparum Dihydroorotate Dehydrogenase (Dhodh) Co-Crystallized With N-(2,2-Diphenylethyl)-4-Hydroxy-1,2,5-Thiadiazole-3-Carboxamide
Organism: Plasmodium falciparum
Method: X-RAY DIFFRACTION Resolution:1.98 Å Release Date: 2018-12-19 Classification: OXIDOREDUCTASE Ligands: FMN, ORO, DZB |
Organism: Plasmodium falciparum
Method: X-RAY DIFFRACTION
Release Date: 2018-12-19
Ligands: FMN, ORO, DZB
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Targeting Myeloid Differentiation Using Potent Human Dihydroorotate Dehydrogenase (Hdhodh) Inhibitors Based On 2-Hydroxypyrazolo[1,5-A]Pyridine Scaffold
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.58 Å Release Date: 2018-07-11 Classification: OXIDOREDUCTASE Ligands: DUH, CL, FMN, ACT, ORO, GOL, PGE |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2018-07-11
Ligands: DUH, CL, FMN, ACT, ORO, GOL, PGE
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Potent And Selective Aldo-Keto Reductase 1C3 (Akr1C3) Inhibitors Based On The Benzoisoxazole Moiety: Application Of A Bioisosteric Scaffold Hopping Approach To Flufenamic Acid
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.88 Å Release Date: 2018-04-04 Classification: OXIDOREDUCTASE Ligands: NAP, CJ2 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2018-04-04
Ligands: NAP, CJ2
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Potent And Selective Aldo-Keto Reductase 1C3 (Akr1C3) Inhibitors Based On The Benzoisoxazole Moiety: Application Of A Bioisosteric Scaffold Hopping Approach To Flufenamic Acid
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.30 Å Release Date: 2018-04-04 Classification: OXIDOREDUCTASE Ligands: CVN, CL, NAP |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2018-04-04
Ligands: CVN, CL, NAP
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Crystal Structure Of Potent Human Dihydroorotate Dehydrogenase Inhibitors Based On Hydroxylated Azole Scaffolds
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.75 Å Release Date: 2017-03-08 Classification: OXIDOREDUCTASE Ligands: FMN, ORO, HYT, ACT, CL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-03-08
Ligands: FMN, ORO, HYT, ACT, CL
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Crystal Structure Of Potent Human Dihydroorotate Dehydrogenase Inhibitors Based On Hydroxylated Azole Scaffolds
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.85 Å Release Date: 2017-03-08 Classification: OXIDOREDUCTASE Ligands: FMN, ORO, Y9B, ACT, CL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-03-08
Ligands: FMN, ORO, Y9B, ACT, CL
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Crystal Structure Of Potent Human Dihydroorotate Dehydrogenase Inhibitors Based On Hydroxylated Azole Scaffolds
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.95 Å Release Date: 2017-03-08 Classification: OXIDOREDUCTASE Ligands: FMN, ORO, U91, ACT, CL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-03-08
Ligands: FMN, ORO, U91, ACT, CL